EC Number | Application | Comment | Organism |
---|---|---|---|
1.14.11.4 | medicine | deficiency in enzyme activity causes the Ehler-Danlos syndrome type 6 | Homo sapiens |
1.14.11.4 | medicine | deficiency in enzyme activity causes the Ehler-Danlos syndrome type 6 | Rattus norvegicus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.11.4 | expression in insect cells using a baculovirus vector | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.11.4 | 0.1 | - |
Procollagen L-lysine | - |
Rattus norvegicus | |
1.14.11.4 | 0.106 | - |
2-oxoglutarate | - |
Rattus norvegicus | |
1.14.11.4 | 0.122 | - |
ascorbate | - |
Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.11.4 | 85000 | - |
x * 85000, SDS-PAGE and Western blotting | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.4 | Gallus gallus | - |
- |
- |
1.14.11.4 | Homo sapiens | - |
- |
- |
1.14.11.4 | Rattus norvegicus | Q63321 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.11.4 | - |
Gallus gallus |
1.14.11.4 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.11.4 | lung | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.11.4 | additional information | - |
- |
Homo sapiens |
1.14.11.4 | additional information | - |
specific activity of the recombinant enzyme three-fold higher than the specific activity of native enzyme | Gallus gallus |
1.14.11.4 | additional information | - |
specific activity of the recombinant enzyme three-fold higher than the specific activity of native enzyme | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.4 | 2-oxoglutarate + O2 + ascorbate | - |
Rattus norvegicus | succinate + CO2 + dehydroascorbate + H2O | - |
? | |
1.14.11.4 | peptidyl-L-lysine + 2-oxoglutarate + O2 | - |
Gallus gallus | peptidyl-5-hydroxy-L-lysine + succinate + CO2 | hydroxy-L-lysine | ? | |
1.14.11.4 | peptidyl-L-lysine + 2-oxoglutarate + O2 | - |
Homo sapiens | peptidyl-5-hydroxy-L-lysine + succinate + CO2 | hydroxy-L-lysine | ? | |
1.14.11.4 | peptidyl-L-lysine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | peptidyl-5-hydroxy-L-lysine + succinate + CO2 | hydroxy-L-lysine | ? | |
1.14.11.4 | [procollagen] L-lysine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | [procollagen]-(2S,5R)-5-hydroxy-L-lysine + succinate + CO2 | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.11.4 | ? | x * 85000, SDS-PAGE and Western blotting | Rattus norvegicus |