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Literature summary extracted from

  • Koyama, H.
    Oxidation and oxygenation of L-amino acids catalyzed by a L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501 (1984), J. Biochem., 96, 421-427.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.12.9 3-Phenylpropionic acid competitive towards L-Phe Pseudomonas sp.
1.13.12.9 4-phenylbutyric acid competitive towards L-Phe Pseudomonas sp.
1.13.12.9 5-phenylpentanoate
-
 Pseudomonas sp.
1.13.12.9 D-Phe
-
 Pseudomonas sp.
1.13.12.9 phenylacetic acid inhibits both oxidation and oxygenation of L-Phe Pseudomonas sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.12.9 0.011
-
 L-Phe oxygenation Pseudomonas sp.
1.13.12.9 0.012
-
 p-fluoro-DL-Phe calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 0.0133
-
 L-Phe oxidation Pseudomonas sp.
1.13.12.9 0.048
-
 DL-m-Tyr
-
 Pseudomonas sp.
1.13.12.9 0.052
-
 beta-2-thienyl-DL-Ala calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 0.189
-
 DL-o-Tyr calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 0.275
-
 L-Tyr calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 0.502
-
 L-Met calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 0.83
-
 L-norleucine calculation from oxygen consumption due to oxidation and/or oxygenation Pseudomonas sp.
1.13.12.9 1.96
-
 O2 oxygenation Pseudomonas sp.
1.13.12.9 2.04
-
 O2 oxidation Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
1.13.12.9 Pseudomonas sp.
-
 P-501
-
1.13.12.9 Pseudomonas sp. P-501
-
 P-501
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.12.9 beta-2-thienyl-DL-Ala + O2
-
 Pseudomonas sp. ? + CO2 + H2O
-
 ?
1.13.12.9 beta-2-thienyl-DL-Ala + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?
1.13.12.9 DL-m-Tyr + O2
-
 Pseudomonas sp. ? + CO2 + H2O
-
 ?
1.13.12.9 DL-m-Tyr + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?
1.13.12.9 DL-o-Tyr + O2
-
 Pseudomonas sp. ? + CO2 + H2O
-
 ?
1.13.12.9 DL-o-Tyr + O2
-
 Pseudomonas sp. P-501 ? + CO2 + H2O
-
 ?
1.13.12.9 DL-o-Tyr + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?
1.13.12.9 L-Met + O2
-
 Pseudomonas sp. 2-oxo-methiolbutyrate + NH3 + H2O2
-
 ?
1.13.12.9 L-norleucine + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?
1.13.12.9 L-Phe + O2
-
 Pseudomonas sp. 2-phenylacetamide + CO2 + H2O
-
 ?
1.13.12.9 L-Phe + O2
-
 Pseudomonas sp. P-501 2-phenylacetamide + CO2 + H2O
-
 ?
1.13.12.9 L-Phe + O2
-
 Pseudomonas sp. beta-phenylpyruvate + NH3 + H2O2
-
 ?
1.13.12.9 L-Phe + O2
-
 Pseudomonas sp. P-501 beta-phenylpyruvate + NH3 + H2O2
-
 ?
1.13.12.9 L-Tyr + O2
-
 Pseudomonas sp. ? + CO2 + H2O
-
 ?
1.13.12.9 L-Tyr + O2
-
 Pseudomonas sp. P-501 ? + CO2 + H2O
-
 ?
1.13.12.9 L-Tyr + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?
1.13.12.9 L-Tyr + O2
-
 Pseudomonas sp. P-501 ? + NH3 + H2O2
-
 ?
1.13.12.9 p-fluoro-DL-Phe + O2
-
 Pseudomonas sp. ? + CO2 + H2O
-
 ?
1.13.12.9 p-fluoro-DL-Phe + O2
-
 Pseudomonas sp. ? + NH3 + H2O2
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.13.12.9 0.017
-
 3-phenylpropanoate
-
 Pseudomonas sp.
1.13.12.9 0.056
-
 4-phenyl-n-butyrate
-
 Pseudomonas sp.
1.13.12.9 0.098
-
 phenylacetic acid
-
 Pseudomonas sp.
1.13.12.9 0.93
-
 5-phenylpentanoate
-
 Pseudomonas sp.
1.13.12.9 7.1
-
 D-Phe
-
 Pseudomonas sp.