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Literature summary extracted from

  • Scandurra, R.; Moriggi, M.; Consalvi, V.; Politi, L.
    Phosphopantothenoylcysteine decarboxylase from horse liver [4'-phospho-N-(D-pantothenoyl)-L-cysteine carboxy-lyase, EC 4.1.1.36] (1979), Methods Enzymol., 62, 245-248.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.36 2-mercaptoethanol increases activity Equus caballus
4.1.1.36 cysteine increases activity Equus caballus
4.1.1.36 DTT increases activity Equus caballus
4.1.1.36 pyruvate covalently bound, involved in catalytic activity Equus caballus
4.1.1.36 Urea 0.2-0.5 M, increases activity Equus caballus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.36 hydroxylamine
-
Equus caballus
4.1.1.36 iodoacetamide
-
Equus caballus
4.1.1.36 NaBH4
-
Equus caballus
4.1.1.36 phenylhydrazine
-
Equus caballus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.36 1.43
-
4-phosphopantothenoyl-L-Cys
-
Equus caballus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.36 Equus caballus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.36
-
Equus caballus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.36 liver
-
Equus caballus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.36 0.089
-
-
Equus caballus

Storage Stability

EC Number Storage Stability Organism
4.1.1.36 -20°C, stable for at least 2 months Equus caballus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.36 N-((R)-4-Phosphopantothenoyl)-L-Cys
-
Equus caballus Pantotheine 4-phosphate + CO2
-
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