EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.49 | DTNB | - |
Trypanosoma cruzi | |
4.1.1.49 | p-chloromercuribenzoate | - |
Trypanosoma cruzi |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.49 | 0.027 | - |
oxaloacetate | - |
Trypanosoma cruzi | |
4.1.1.49 | 0.039 | - |
ADP | ADP in form of MgADP- | Trypanosoma cruzi | |
4.1.1.49 | 0.36 | - |
phosphoenolpyruvate | - |
Trypanosoma cruzi | |
4.1.1.49 | 3.7 | - |
CO2 | CO2 in form of HCO3- | Trypanosoma cruzi |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.49 | Mn2+ | one Mn2+ is required for the activation of each 42000 Da subunit | Trypanosoma cruzi | |
4.1.1.49 | Mn2+ | strictly dependent on | Trypanosoma cruzi |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.1.1.49 | 42000 | - |
2 * 42000, SDS-PAGE | Trypanosoma cruzi |
4.1.1.49 | 82000 | - |
gel filtration | Trypanosoma cruzi |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.49 | additional information | Trypanosoma cruzi | important regulatory function of the enzyme in the amino-acid catabolism of Trypanosoma cruzi | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.49 | Trypanosoma cruzi | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.1.49 | - |
Trypanosoma cruzi |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.1.1.49 | epimastigote | - |
Trypanosoma cruzi | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.1.1.49 | additional information | - |
- |
Trypanosoma cruzi |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 | - |
Trypanosoma cruzi | ATP + oxaloacetate | - |
? | |
4.1.1.49 | additional information | important regulatory function of the enzyme in the amino-acid catabolism of Trypanosoma cruzi | Trypanosoma cruzi | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.1.1.49 | dimer | 2 * 42000, SDS-PAGE | Trypanosoma cruzi |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.1.1.49 | 6.9 | - |
carboxylation | Trypanosoma cruzi |
4.1.1.49 | 8 | - |
decarboxylation | Trypanosoma cruzi |