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Literature summary extracted from

  • Pösö, H.; Sinervirta, R.; Jänne, J.
    S-Adenosylmethionine decarboxylase from baker's yeast (1975), Biochem. J., 151, 67-73.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.50 1,3-diaminopropane stimulates Saccharomyces cerevisiae
4.1.1.50 1,5-Diaminopentane stimulates Saccharomyces cerevisiae
4.1.1.50 cadaverine activates Saccharomyces cerevisiae
4.1.1.50 putrescine stimulation Saccharomyces cerevisiae
4.1.1.50 spermidine stimulates Saccharomyces cerevisiae
4.1.1.50 spermine weak stimulation Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
-
 Saccharomyces cerevisiae
4.1.1.50 4-Bromo-3-hydroxybenzyloxyamine
-
 Saccharomyces cerevisiae
4.1.1.50 Canaline at high concentrations Saccharomyces cerevisiae
4.1.1.50 Isonicotinic acid hydrazide at high concentrations Saccharomyces cerevisiae
4.1.1.50 methylglyoxal bis(guanylhydrazone) strong Saccharomyces cerevisiae
4.1.1.50 S-adenosyl-L-methionine in presence of saturating concentrations of putrescine Saccharomyces cerevisiae
4.1.1.50 S-methyladenosylhomocysteamine strong Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.50 0.09
-
 S-adenosylmethionine in presence of putrescine Saccharomyces cerevisiae
4.1.1.50 0.5
-
 S-adenosylmethionine in absence of putrescine Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.50
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.50 additional information
-
-
 Saccharomyces cerevisiae

Storage Stability

EC Number Storage Stability Organism
4.1.1.50 -20°C, 20 mM Tris-HCl, 1 mM EDTA, pH 7.4, stable for up to 2 months Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 S-adenosyl-L-methionine
-
 Saccharomyces cerevisiae (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?