Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Feldman, M.J.; Levy, C.C.; Rusell, D.H.
    Purification and characterization of S-adenosyl-L-methionine decarboxylase from rat liver (1972), Biochemistry, 11, 671-677.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.50 putrescine stimulation Rattus norvegicus
4.1.1.50 spermidine stimulates Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 Ca2+
-
 Rattus norvegicus
4.1.1.50 Cd2+
-
 Rattus norvegicus
4.1.1.50 NEM
-
 Rattus norvegicus
4.1.1.50 p-chloromercuribenzoate
-
 Rattus norvegicus
4.1.1.50 Zn2+
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.50 0.036
-
 S-adenosyl-L-methionine
-
 Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.50 additional information no requirement for a divalent metal ion Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.50 44000
-
 liver, gel filtration Rattus norvegicus
4.1.1.50 47000
-
 uterus, gel filtration Rattus norvegicus
4.1.1.50 52000
-
 liver, sucrose density gradient centrifugation Rattus norvegicus
4.1.1.50 52000
-
 prostate, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.50
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.50 liver
-
 Rattus norvegicus
-
4.1.1.50 prostate gland ventral Rattus norvegicus
-
4.1.1.50 uterus
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.50 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 S-adenosyl-L-methionine
-
 Rattus norvegicus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.50 7.2
-
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.50 pyridoxal 5'-phosphate cofactor Rattus norvegicus