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Literature summary extracted from

  • Buckner, J.S.; Kolattukudy, P.E.; Poulose, A.J.
    Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose (1976), Arch. Biochem. Biophys., 177, 539-551.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.9 2,2'-dipyridyl
-
 Anser sp.
4.1.1.9 3-Bromopyruvate
-
 Anser sp.
4.1.1.9 acetyl-CoA
-
 Anser sp.
4.1.1.9 Avidin 0.6 mg/ml, 11% inhibition Anser sp.
4.1.1.9 CoA
-
 Anser sp.
4.1.1.9 EDTA 1 mM, 15% inhibition Anser sp.
4.1.1.9 methylmalonyl-CoA
-
 Anser sp.
4.1.1.9 NEM
-
 Anser sp.
4.1.1.9 p-hydroxymercuribenzoate
-
 Anser sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.9 0.1
-
 malonyl-CoA
-
 Anser sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.9 additional information no metal ion participation Anser sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.9 47000
-
 4 * 47000, SDS-PAGE Anser sp.
4.1.1.9 186000
-
 equilibrium sedimentation Anser sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.9 Malonyl-CoA Anser sp. discussion of the probable role of the enzyme in the regulation of lipid metabolism, especially branched-chain fatty acid synthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.9 Anser sp.
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.9
-
 Anser sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.9 uropygial gland
-
 Anser sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.9 74
-
-
 Anser sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.9 Malonyl-CoA
-
 Anser sp. Acetyl-CoA + CO2
-
 ?
4.1.1.9 Malonyl-CoA discussion of the probable role of the enzyme in the regulation of lipid metabolism, especially branched-chain fatty acid synthesis Anser sp. ?
-
 ?
4.1.1.9 methylmalonyl-CoA at less than 7% of the activity with malonyl-CoA Anser sp. propionyl-CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.9 tetramer 4 * 47000, SDS-PAGE Anser sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.9 9.5
-
-
 Anser sp.