Literature summary extracted from

Braissant, O.; Henry, H.; Loup, M.; Eilers, B.; Bachmann, C.
Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study (2001), Mol. Brain Res., 86, 193-201.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.1.1.2	nucleus	perinuclear localization	Rattus norvegicus	5634	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.2	S-adenosyl-L-methionine + guanidinoacetate	Rattus norvegicus	-	S-adenosyl-L-homocysteine + creatine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.2	Rattus norvegicus	P10868	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.2	brain	all parts of brain, neurons and glia, very low levels in astrocytes	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.2	S-adenosyl-L-methionine + guanidinoacetate	-	Rattus norvegicus	S-adenosyl-L-homocysteine + creatine	-	?

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Release 2023.1 (January 2023)