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Literature summary extracted from

  • Coleman, R.A.
    Diacylglycerol acyltransferase and monoacylglycerol acyltransferase from liver and intestine (1992), Methods Enzymol., 209, 98-104.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.20 microsome intrinsic membrane protein Rattus norvegicus
-
-
2.3.1.20 microsome active site on cytoplasmic surface Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.20 acyl-CoA + 1,2-diacylglycerol Rattus norvegicus last reaction in triacylglycerol synthesis CoA + triacylglycerol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.20 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.20 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.20 adipocyte isolated from parametrial adipose Rattus norvegicus
-
2.3.1.20 intestinal mucosa high activity Rattus norvegicus
-
2.3.1.20 liver
-
 Rattus norvegicus
-
2.3.1.20 mammary gland high activity Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.20 additional information
-
 specific activity in the nanomolar range in microsomal preparations, varies considerably between different tissues Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.20 acyl-CoA + 1,2-diacylglycerol saturated fatty acyl-CoAs from C-8 to C-12 Rattus norvegicus CoA + triacylglycerol
-
 ?
2.3.1.20 acyl-CoA + 1,2-diacylglycerol 2,3-diacylglycerol is acylated at 20% the rate of 1,2-isomer Rattus norvegicus CoA + triacylglycerol
-
 ?
2.3.1.20 acyl-CoA + 1,2-diacylglycerol last reaction in triacylglycerol synthesis Rattus norvegicus CoA + triacylglycerol
-
 ?
2.3.1.20 palmitoyl-CoA + 1,2-diacylglycerol
-
 Rattus norvegicus CoA + 1,2-diacyl-3-palmitoylglycerol
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.20 additional information
-
 assay at various temperatures from 24°C to 40°C Rattus norvegicus
2.3.1.20 25
-
 assay at Rattus norvegicus