Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Murray, I.A.; Martinez-Suarez, J.V.; Close, T.J.; Shaw, W.V.
    Nucleotide sequences of genes encoding the type II chloramphenicol acetyltransferases of Escherichia coli and Haemophilus influenzae, which are sensitive to inhibition by thiol-reactive reagents (1990), Biochem. J., 272, 505-510.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.28
-
 Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.28 4,4'-dithiodipyridine
-
 Escherichia coli
2.3.1.28 5,5'-dithiobis(2-nitrobenzoic acid)
-
 Escherichia coli
2.3.1.28 methyl methanethiolsulfonate
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.28 0.0103
-
 chloramphenicol
-
 Escherichia coli
2.3.1.28 0.065
-
 acetyl-CoA
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.28 Escherichia coli
-
 CATII is encoded by the IncW transmissible plasmid pSA
-
2.3.1.28 Haemophilus influenzae
-
 CATII
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.28 acetyl-CoA + chloramphenicol
-
 Haemophilus influenzae CoA + chloramphenicol 3-acetate
-
 ?
2.3.1.28 acetyl-CoA + chloramphenicol
-
 Escherichia coli CoA + chloramphenicol 3-acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.28 CAT II enzyme encoded by the incW transmissible plasmid Haemophilus influenzae
2.3.1.28 CAT II enzyme encoded by the incW transmissible plasmid Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.3.1.28 additional information
-
 additional information
-
 Escherichia coli