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Literature summary extracted from

  • Emson, P.C.; Malthe-Soerenssen, D.; Fonnum, F.
    Purification and properties of choline acetyltransferase from the nervous system of different invertebrates (1974), J. Neurochem., 22, 1089-1098.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.6 KCl
-
 Limulus polyphemus
2.3.1.6 KCl
-
 Cornu aspersum
2.3.1.6 KCl
-
 Periplaneta americana
2.3.1.6 NaCl
-
 Limulus polyphemus
2.3.1.6 NaCl
-
 Cornu aspersum
2.3.1.6 NaCl
-
 Periplaneta americana

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.6 3-Bromoacetonyltrimethylammonium ion
-
 Cornu aspersum
2.3.1.6 3-Bromoacetonyltrimethylammonium ion
-
 Limulus polyphemus
2.3.1.6 3-Bromoacetonyltrimethylammonium ion
-
 Periplaneta americana
2.3.1.6 5,5'-dithiobis(2-nitrobenzoate)
-
 Cornu aspersum
2.3.1.6 5,5'-dithiobis(2-nitrobenzoate)
-
 Limulus polyphemus
2.3.1.6 5,5'-dithiobis(2-nitrobenzoate)
-
 Periplaneta americana
2.3.1.6 Acetylcholine competitive to choline, non-competitive to acetyl-CoA Cornu aspersum
2.3.1.6 Acetylcholine competitive to choline, non-competitive to acetyl-CoA Limulus polyphemus
2.3.1.6 Acetylcholine competitive to choline, non-competitive to acetyl-CoA Periplaneta americana
2.3.1.6 Acyloylcholine
-
 Cornu aspersum
2.3.1.6 Acyloylcholine
-
 Limulus polyphemus
2.3.1.6 Acyloylcholine
-
 Periplaneta americana
2.3.1.6 Chloroacetylcholine
-
 Cornu aspersum
2.3.1.6 Chloroacetylcholine
-
 Limulus polyphemus
2.3.1.6 Chloroacetylcholine
-
 Periplaneta americana
2.3.1.6 CoA competitive to acetyl-CoA, non-competitive to choline Cornu aspersum
2.3.1.6 CoA competitive to acetyl-CoA, non-competitive to choline Limulus polyphemus
2.3.1.6 CoA competitive to acetyl-CoA, non-competitive to choline Periplaneta americana
2.3.1.6 iodoacetate
-
 Cornu aspersum
2.3.1.6 iodoacetate
-
 Limulus polyphemus
2.3.1.6 iodoacetate
-
 Periplaneta americana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.6 0.016
-
 acetyl-CoA
-
 Periplaneta americana
2.3.1.6 0.051
-
 acetyl-CoA
-
 Cornu aspersum
2.3.1.6 0.068
-
 acetyl-CoA
-
 Limulus polyphemus
2.3.1.6 0.37
-
 choline
-
 Cornu aspersum
2.3.1.6 0.55
-
 choline
-
 Periplaneta americana
2.3.1.6 27
-
 choline
-
 Limulus polyphemus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Cornu aspersum
-
 snail
-
2.3.1.6 Limulus polyphemus
-
 horseshoe crab
-
2.3.1.6 Periplaneta americana
-
 cockroach
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.6
-
 Limulus polyphemus
2.3.1.6
-
 Cornu aspersum
2.3.1.6
-
 Periplaneta americana

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Limulus polyphemus acetylcholine + CoA
-
 ?
2.3.1.6 acetyl-CoA + choline
-
 Cornu aspersum acetylcholine + CoA
-
 ?
2.3.1.6 acetyl-CoA + choline
-
 Periplaneta americana acetylcholine + CoA
-
 ?