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Literature summary extracted from

  • Croteau, R.; Hooper, C.L.
    Metabolism of monoterpenes. Acetylation of (-)-menthol by a soluble enzyme preparation from peppermint (Mentha piperita) leaves (1978), Plant Physiol., 61, 737-742.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.69 dithioerythritol required for maximal activity Mentha x piperita

General Stability

EC Number General Stability Organism
2.3.1.69 dithioerythritol, required for maximal stability Mentha x piperita

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.69 diisopropylfluorophosphate strong inhibitor, 50% inhibition at 0.1 mM Mentha x piperita
2.3.1.69 EDTA slightly inhibitory Mentha x piperita
2.3.1.69 p-hydroxymercuribenzoate
-
 Mentha x piperita

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.69 0.2
-
 (-)-menthol flower head enzyme Mentha x piperita
2.3.1.69 0.3
-
 (-)-menthol leaf enzyme Mentha x piperita

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.69 soluble 100000 g supernatant fraction Mentha x piperita
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.69 37000
-
 gel filtration Mentha x piperita

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.69 Mentha x piperita
-
 peppermint
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.69 partial Mentha x piperita

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.69 flower
-
 Mentha x piperita
-
2.3.1.69 leaf
-
 Mentha x piperita
-

Storage Stability

EC Number Storage Stability Organism
2.3.1.69 0°C, 5 mM dithioerythritol, 15% glycerol, 60% loss of activity after 24 h Mentha x piperita

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.69 (+)-2-terpineol + acetyl-CoA low activity Mentha x piperita CoA + (+)-2-terpineol acetate
-
 ?
2.3.1.69 (+)-isomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (+)-isomenthol acetate
-
 ?
2.3.1.69 (+)-menthol + acetyl-CoA
-
 Mentha x piperita CoA + (+)-menthol acetate
-
 ?
2.3.1.69 (+)-neoisomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (+)-neoisomenthol acetate
-
 ?
2.3.1.69 (-)-isomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (-)-isomenthol acetate
-
 ?
2.3.1.69 (-)-neoisomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (-)-neoisomenthol acetate
-
 ?
2.3.1.69 (-)-neomenthol + acetyl-CoA
-
 Mentha x piperita CoA + (-)-neomenthol acetate
-
 ?
2.3.1.69 acetyl-CoA + (+)-neomenthol
-
 Mentha x piperita CoA + neomenthyl acetate
-
 ?
2.3.1.69 acetyl-CoA + (-)-menthol
-
 Mentha x piperita CoA + (-)-menthyl acetate
-
 ?
2.3.1.69 acetyl-CoA + borneol
-
 Mentha x piperita CoA + borneol acetate
-
 ?
2.3.1.69 acetyl-CoA + cyclohexanol
-
 Mentha x piperita CoA + cyclohexanol acetate
-
 ?
2.3.1.69 acetyl-CoA + n-decanol best substrate Mentha x piperita CoA + n-decanol acetate
-
 ?
2.3.1.69 additional information specific for acetyl-CoA, propionyl-CoA reacts with 11% of the activity of acetyl-CoA, butyryl-CoA reacts with 2% of the activity of acetyl-CoA, enzyme has a slight preference for stereomers in which the hydroxyl and isopropyl are cis located Mentha x piperita ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.69 9
-
-
 Mentha x piperita

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.69 7.5 10 pH 7.5: about 50% of activity maximum, increase of activity up to pH 9.5, pH 10: about 40% of activity maximum Mentha x piperita