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Literature summary extracted from

  • Ueda, M.; Tanaka, A.; Fukui, S.
    Peroxisomal and mitochondrial carnitine acetyltransferases in alkane-grown yeast Candida tropicalis (1982), Eur. J. Biochem., 124, 205-210.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.7 inactivated under the conditions of freeze/thaw Candida tropicalis

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.7 5,5'-dithio-bis(2-nitrobenzoic acid)
-
 Rattus norvegicus
2.3.1.7 5,5'-dithio-bis(2-nitrobenzoic acid)
-
 Sus scrofa
2.3.1.7 Ca2+
-
 Candida tropicalis
2.3.1.7 Mg2+
-
 Candida tropicalis
2.3.1.7 p-chloromercuribenzoic acid
-
 Candida tropicalis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.7 0.036
-
 acetyl-CoA mitochondrial enzyme Candida tropicalis
2.3.1.7 0.042
-
 acetyl-CoA peroxisomal enzyme Candida tropicalis
2.3.1.7 0.1
-
 propionyl-CoA peroxisomal enzyme Candida tropicalis
2.3.1.7 0.162
-
 propionyl-CoA mitochondrial enzyme Candida tropicalis
2.3.1.7 0.257
-
 CoASH mitochondrial enzyme Candida tropicalis
2.3.1.7 0.304
-
 CoASH peroxisomal enzyme Candida tropicalis
2.3.1.7 0.417
-
 acetylcarnitine peroxisomal enzyme Candida tropicalis
2.3.1.7 0.622
-
 L-carnitine mitochondrial enzyme, second substrate acetyl-CoA Candida tropicalis
2.3.1.7 0.639
-
 acetylcarnitine mitochondrial enzyme Candida tropicalis
2.3.1.7 0.655
-
 L-carnitine peroxisomal enzyme, second substrate propionyl-CoA Candida tropicalis
2.3.1.7 0.719
-
 L-carnitine peroxisomal enzyme, second substrate acetyl-CoA Candida tropicalis
2.3.1.7 0.774
-
 L-carnitine mitochondrial enzyme, second substrate propionyl-CoA Candida tropicalis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.7 microsome
-
 Rattus norvegicus
-
-
2.3.1.7 microsome
-
 Candida tropicalis
-
-
2.3.1.7 microsome
-
 Columba sp.
-
-
2.3.1.7 mitochondrion
-
 Rattus norvegicus 5739
-
2.3.1.7 mitochondrion
-
 Candida tropicalis 5739
-
2.3.1.7 peroxisome
-
 Rattus norvegicus 5777
-
2.3.1.7 peroxisome
-
 Candida tropicalis 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine Rattus norvegicus
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Sus scrofa
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Candida tropicalis
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Columba sp.
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Rattus norvegicus
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Sus scrofa
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Candida tropicalis
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Columba sp.
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH Rattus norvegicus
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Sus scrofa
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Candida tropicalis
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Columba sp.
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Rattus norvegicus
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Sus scrofa
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Candida tropicalis
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Columba sp.
-
 acetyl-CoA + carnitine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.7 Candida tropicalis
-
 yeast
-
2.3.1.7 Candida tropicalis
-
 (Castellani) Berkhout strain pK233(ATCC 20336)
-
2.3.1.7 Columba sp.
-
 pigeon
-
2.3.1.7 Rattus norvegicus
-
 rat
-
2.3.1.7 Sus scrofa
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.7 mitochondrial and peroxisomal enzyme Candida tropicalis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.7 breast muscle
-
 Columba sp.
-
2.3.1.7 liver
-
 Rattus norvegicus
-
2.3.1.7 liver
-
 Columba sp.
-
2.3.1.7 muscle
-
 Rattus norvegicus
-
2.3.1.7 muscle
-
 Columba sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.7 88.5
-
 peroxisomal enzyme Candida tropicalis
2.3.1.7 113
-
-
 Candida tropicalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine
-
 Rattus norvegicus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Sus scrofa O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Candida tropicalis O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Rattus norvegicus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Sus scrofa O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Candida tropicalis O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Rattus norvegicus acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Sus scrofa acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Candida tropicalis acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Columba sp. acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Rattus norvegicus acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Sus scrofa acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Candida tropicalis acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Columba sp. acyl-CoA + carnitine
-
 r
2.3.1.7 decanoyl-CoA + carnitine
-
 Rattus norvegicus decanoylcarnitine + CoASH
-
 r
2.3.1.7 decanoyl-CoA + carnitine
-
 Sus scrofa decanoylcarnitine + CoASH
-
 r
2.3.1.7 decanoyl-CoA + carnitine
-
 Columba sp. decanoylcarnitine + CoASH
-
 r
2.3.1.7 decanoylcarnitine + CoASH
-
 Rattus norvegicus decanoyl-CoA + carnitine
-
 r
2.3.1.7 decanoylcarnitine + CoASH
-
 Sus scrofa decanoyl-CoA + carnitine
-
 r
2.3.1.7 decanoylcarnitine + CoASH
-
 Columba sp. decanoyl-CoA + carnitine
-
 r
2.3.1.7 hexanoyl-CoA + carnitine
-
 Rattus norvegicus hexanoylcarnitine + CoASH
-
 r
2.3.1.7 hexanoyl-CoA + carnitine
-
 Sus scrofa hexanoylcarnitine + CoASH
-
 r
2.3.1.7 hexanoyl-CoA + carnitine
-
 Columba sp. hexanoylcarnitine + CoASH
-
 r
2.3.1.7 hexanoylcarnitine + CoASH
-
 Rattus norvegicus hexanoyl-CoA + carnitine
-
 r
2.3.1.7 hexanoylcarnitine + CoASH
-
 Sus scrofa hexanoyl-CoA + carnitine
-
 r
2.3.1.7 hexanoylcarnitine + CoASH
-
 Columba sp. hexanoyl-CoA + carnitine
-
 r
2.3.1.7 additional information
-
 Rattus norvegicus ?
-
 ?
2.3.1.7 additional information
-
 Sus scrofa ?
-
 ?
2.3.1.7 additional information
-
 Columba sp. ?
-
 ?
2.3.1.7 additional information pentanoyl-CoA, hexanoyl-CoA, decanoyl-CoA and palmitoyl-CoA are no substrates Candida tropicalis ?
-
 ?
2.3.1.7 O-acetylcarnitine + CoASH
-
 Rattus norvegicus acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Sus scrofa acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Candida tropicalis acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Rattus norvegicus acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Sus scrofa acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Candida tropicalis acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + carnitine
-
 r
2.3.1.7 propionyl-CoA + L-(-)carnitine
-
 Rattus norvegicus propionylcarnitine + CoASH
-
 r
2.3.1.7 propionyl-CoA + L-(-)carnitine
-
 Candida tropicalis propionylcarnitine + CoASH
-
 r
2.3.1.7 propionylcarnitine + CoASH
-
 Rattus norvegicus propionyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 propionylcarnitine + CoASH
-
 Candida tropicalis propionyl-CoA + L-(-)carnitine
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.7 8
-
-
 Rattus norvegicus
2.3.1.7 8
-
-
 Candida tropicalis