Literature summary extracted from

Duran, A.; Cabib, E.
Solubilization and partial purification of yeast chitin synthetase. Confirmation of the zymogenic nature of the enzyme (1978), J. Biol. Chem., 253, 4419-4425.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.4.1.16	lysophosphatidylserine	required, phosphatidylserine and lysophosphatidylserine are the best activators	Saccharomyces cerevisiae
2.4.1.16	phosphatidylserine	required, phosphatidylserine and lysophosphatidylserine are the best activators	Saccharomyces cerevisiae
2.4.1.16	Phospholipid	required, phosphatidylserine and lysophosphatidylserine are the best activators	Saccharomyces cerevisiae

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.1.16	Polyoxin D	-	Saccharomyces cerevisiae
2.4.1.16	UDP	-	Saccharomyces cerevisiae

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.4.1.16	1.5	-	UDP-N-acetylglucosamine	-	Saccharomyces cerevisiae

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.4.1.16	plasma membrane	-	Saccharomyces cerevisiae	5886	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.16	Aspergillus flavus	-	-	-
2.4.1.16	Saccharomyces cerevisiae	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
2.4.1.16	proteolytic modification	enzyme exists as a zymogen	Saccharomyces cerevisiae

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.4.1.16	partial	Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.4.1.16	additional information	-	-	Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.1.16	UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n	-	Saccharomyces cerevisiae	UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1	-	?
2.4.1.16	UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n	-	Aspergillus flavus	UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.4.1.16	0.001	-	Polyoxin D	-	Saccharomyces cerevisiae
2.4.1.16	2	-	UDP	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)