Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Amado, M.; Almeida, R.; Carneiro, F.; Levery, S.B.; Holmes, E.H.; Nomoto, M.; Hollingsworth, M.A.; Hassan, H.; Schwientek, T.; Nielsen, P.A.; Bennett, E.P.; Clausen, H.
    A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-acetyl-galactosamine beta-1,3-galactosyltransferase family (1998), J. Biol. Chem., 273, 12770-12778.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.62 amino acid sequence determination, expression in Sf9 insect cells via baculovirus transfection Homo sapiens
2.4.1.62 cloning and DNA sequencing, amino acid sequence determination, expression in Sf9 insect cells via baculovirus transfection Homo sapiens
2.4.1.122 functional expression in Spodoptera frugiperda Sf9cells via baculovirus infection Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.62 additional information
-
 amino acid sequence alignment Homo sapiens
2.4.1.62 additional information
-
 amino acid sequence alignment Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.62 Drosophila melanogaster Q24157
-
-
2.4.1.62 Homo sapiens O43825 isoform beta3Gal-T2
-
2.4.1.62 Homo sapiens O75752 isoform beta3Gal-T4
-
2.4.1.62 Homo sapiens O96024 isoform beta3Gal-T1
-
2.4.1.62 Homo sapiens O96024 isoform beta3Gal-T3
-
2.4.1.122 Homo sapiens
-
 EST clone, contains full length sequence
-
2.4.1.122 Homo sapiens O75752
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.62 glycoprotein glycosylation sites, overview Homo sapiens
2.4.1.62 glycoprotein glycosylation sites, overview Drosophila melanogaster

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.62 brain
-
 Homo sapiens
-
2.4.1.62 heart
-
 Homo sapiens
-
2.4.1.62 additional information widely distributed Homo sapiens
-
2.4.1.122 brain low content Homo sapiens
-
2.4.1.122 heart
-
 Homo sapiens
-
2.4.1.122 kidney low content Homo sapiens
-
2.4.1.122 liver
-
 Homo sapiens
-
2.4.1.122 lung
-
 Homo sapiens
-
2.4.1.122 pancreas
-
 Homo sapiens
-
2.4.1.122 placenta
-
 Homo sapiens
-
2.4.1.122 skeletal muscle
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.62 additional information
-
-
 Homo sapiens
2.4.1.122 0.0000028
-
 recombinant in Sf9 cells Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.62 UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine donor and acceptor specificity, overview Homo sapiens UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine
-
 ?
2.4.1.122 additional information no acceptor substrates: ovalbumin, beta-N-acetyl-D-glucosaminyl-benzyl Homo sapiens ?
-
 ?
2.4.1.122 UDP-galactose + ganglioside Gg3 i.e. GalNAcbeta1,4-Galbeta1,4-Glcbeta1-ceramide Homo sapiens UDP + galactosyl-beta-1,3-ganglioside Gg3
-
 ?
2.4.1.122 UDP-galactose + ganglioside GM2 i.e. GalNAcbeta1,4-(NeuAcalpha-2,3-)Galbeta1,4-Glcbeta1-ceramide Homo sapiens UDP + galactosyl-beta-1,3-ganglioside GM2 i.e. ganglioside GM1 ?
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine
-
 Homo sapiens UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.62 beta3Gal-T
-
 Homo sapiens
2.4.1.62 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase
-
 Homo sapiens
2.4.1.122 3betaGal-T4
-
 Homo sapiens