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Literature summary extracted from

  • Kreppel, L.K.; Blomberg, M.A.; Hart, G.W.
    Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats (1997), J. Biol. Chem., 272, 9308-9315.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.255 overexpression of the Ogt gene encoding the 110 kDa alpha-subunit in Escherichia coli and transiently in HEK293 cells, DNA sequence analysis: gene Ogt is no member of a multigene family, the sequence contains multiple tandem repeats of the tetratricopeptide repeat motif Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.255 cytosol unlike previously described glycosyltransferases, OGT is localized to the cytosol and nucleus Rattus norvegicus 5829
-
2.4.1.255 nucleus unlike previously described glycosyltransferases, OGT is localized to the cytosol and nucleus Rattus norvegicus 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.255 78000
-
2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus
2.4.1.255 110000
-
2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.255 Rattus norvegicus P56558
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.255
-
Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.255 brain
-
Rattus norvegicus
-
2.4.1.255 heart
-
Rattus norvegicus
-
2.4.1.255 kidney
-
Rattus norvegicus
-
2.4.1.255 liver
-
Rattus norvegicus
-
2.4.1.255 lung
-
Rattus norvegicus
-
2.4.1.255 muscle
-
Rattus norvegicus
-
2.4.1.255 ovary
-
Rattus norvegicus
-
2.4.1.255 spleen
-
Rattus norvegicus
-
2.4.1.255 thymus
-
Rattus norvegicus
-
2.4.1.255 uterus
-
Rattus norvegicus
-

Subunits

EC Number Subunits Comment Organism
2.4.1.255 heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
2.4.1.255 O-GlcNAc transferase
-
Rattus norvegicus
2.4.1.255 OGT
-
Rattus norvegicus