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Literature summary extracted from

  • Burnett, P.E.; Blackshaw, S.; Lai, M.M.; Qureshi, I.A.; Burnett, A.F.; Sabatini, D.M.; Snyder, S.H.
    Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton (1998), Proc. Natl. Acad. Sci. USA, 95, 8351-8356.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.1 neurabin by way of its PDZ domain, the neuronal-specific neurabin may target p70(S6k) to nerve terminals Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.1 ATP + S6 protein of the 40s ribosomal subunit Rattus norvegicus the mitogen-activated protein kinase plays a central role in the control of mRNA translation. It physiologically phosphorylates the S6 protein of the 40s ribosomal subunit in response to mitogenic stimuli and is a downstream component of the rapamycin-sensitive pathway, which includes the 12-kDa FK506 binding protein and includes rapamycin and the 12-kDa FK506 binding protein target 1 ADP + phosphorylated S6 protein of the 40s ribosomal subunit
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Rattus norvegicus P67999
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 ATP + S6 protein of the 40s ribosomal subunit the mitogen-activated protein kinase plays a central role in the control of mRNA translation. It physiologically phosphorylates the S6 protein of the 40s ribosomal subunit in response to mitogenic stimuli and is a downstream component of the rapamycin-sensitive pathway, which includes the 12-kDa FK506 binding protein and includes rapamycin and the 12-kDa FK506 binding protein target 1 Rattus norvegicus ADP + phosphorylated S6 protein of the 40s ribosomal subunit
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 p70 S6 kinase
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 Rattus norvegicus
2.7.11.1 p70(S6k)
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 Rattus norvegicus
2.7.11.1 ribosomal protein S6 kinase
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 Rattus norvegicus