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Literature summary extracted from

  • Cheng, A.; Fitzgerald, T.J.; Carlson, G.M.
    Adenosine 5-diphosphate as an allosteric effector of phosphorylase kinase from rabbit skeletal muscle (1985), J. Biol. Chem., 260, 2535-2542.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.19 adenosine 3'-phosphate 5'-phosphosulfate activation, can replace ADP to some extent Oryctolagus cuniculus
2.7.11.19 adenosine 5'-phosphosulfate activation, can replace ADP to some extent Oryctolagus cuniculus
2.7.11.19 additional information no activation by g adenine, adenosine, 5'-AMP, 2',5'-ADP, 3',5'-ADP, adenosine 2':3'cyclicphosphate 5'-monophosphate, alpha,beta-methylene-ADP, adenosine 2'-phosphate 5'-phosphosulfate, adenosine 5'-diphosphoglucose, adenosine 5'-diphosphoribose, ADP-3'-diphosphate, adenylylimidodiphosphate, diadenosine diphosphate Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.19 Mg2+ requirement Oryctolagus cuniculus
2.7.11.19 Mg2+ major role of Mg2+: cosubstrate in Mg2+-ATP complex Oryctolagus cuniculus
2.7.11.19 phosphate requirement, phosphate containing enzyme Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.19 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.19 skeletal muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.19 ATP + phosphorylase b cosubstrate: Mg-ATP complex Oryctolagus cuniculus ADP + phosphorylase a
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.19 2'-deoxy-ADP activation, can replace ADP Oryctolagus cuniculus
2.7.11.19 ADP kinetics, 8 binding sites per hexadecamer Oryctolagus cuniculus
2.7.11.19 ADP allosteric effector Oryctolagus cuniculus