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Literature summary extracted from

  • Hilderman, R.H.
    Characterization of a homogeneous complex of arginyl- and lysyl-tRNA synthetase. Zinc and adenosine 5'-phosphate dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (1983), Biochemistry, 22, 4353-4357.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.1.1.6 AMP stimulation of diadenosine 5',5'''-P1,P4-tetraphosphate synthetase activity Rattus norvegicus
6.1.1.6 Diphosphatase stimulation of diadenosine 5',5'''-P1,P4-tetraphosphate synthetase activity Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1.1.6 1.5
-
 AMP 5',5'''-P1,P4-tetraphosphate formation Rattus norvegicus
6.1.1.6 2.1
-
 ATP 5',5'''-P1,P4-tetraphosphate formation Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.6 Zn2+ stimulation of diadenosine 5',5'''-P1,P4-tetraphosphate synthetase activity Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.6 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.6 AMP + ATP
-
 Rattus norvegicus diadenosine 5',5''-P1,P4-tetraphosphate + ?
-
 ?
6.1.1.6 ATP + lysine + tRNALys
-
 Rattus norvegicus AMP + L-lysyl-tRNALys + diphosphate
-
 ?
6.1.1.6 additional information L-lysine-dependent synthesis of 5',5'-diadenosine tetraphosphate (Ap4A) Rattus norvegicus ?
-
 ?