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Literature summary extracted from

  • Gerlinger, E.; Retey, J.
    Proposal for the mechanism of action of urocanase. Interference from the inhibition by 2-methylurocanate (1987), Z. Naturforsch. C, 42, 349-352.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.49 2-Methylimidazolone propionate
-
 Pseudomonas putida
4.2.1.49 2-Methylurocanate
-
 Pseudomonas putida
4.2.1.49 hydroxylamine
-
 Pseudomonas putida
4.2.1.49 Imidazolepropionate competitive Pseudomonas putida
4.2.1.49 NaBH4
-
 Pseudomonas putida
4.2.1.49 O-Methylhydroxylamine
-
 Pseudomonas putida
4.2.1.49 Sodium dithionite
-
 Pseudomonas putida
4.2.1.49 sulfite
-
 Pseudomonas putida

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.49 Urocanate + H2O Pseudomonas putida
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.49 Pseudomonas putida
-
 ATCC 11299
-

Reaction

EC Number Reaction Comment Organism Reaction ID
4.2.1.49 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O reaction mechanism Pseudomonas putida
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.49 2-Methylurocanate + H2O
-
 Pseudomonas putida 2-Methylimidazolone propionate
-
 ?
4.2.1.49 Urocanate + H2O
-
 Pseudomonas putida 4,5-Dihydro-4-oxo-5-imidazolepropanoate
-
 ?
4.2.1.49 Urocanate + H2O
-
 Pseudomonas putida ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.1.49 NAD+
-
 Pseudomonas putida