Literature summary extracted from

Lippert, B.; Metcalf, B.W.; Jung, M.J.; Casara, P.
4-Amino-hex-5-enoic acid, a selective catalytic inhibitor of 4-aminobutyric-acid aminotransferase in mammalian brain (1977), Eur. J. Biochem., 74, 441-445.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.6.1.19	4-Amino-hex-5-enoic acid	substrate analogue, irreversible, in vitro and in vivo	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.6.1.19	Pseudomonas fluorescens	-	-	-
2.6.1.19	Rattus norvegicus	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
2.6.1.19	4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate	mechanism	Rattus norvegicus	a
2.6.1.19	4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate	mechanism	Pseudomonas fluorescens	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.6.1.19	brain	-	Rattus norvegicus	-
2.6.1.19	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.6.1.19	4-aminobutanoate + 2-oxoglutarate	-	Rattus norvegicus	4-oxobutanoate + L-glutamate	-	r
2.6.1.19	4-aminobutanoate + 2-oxoglutarate	-	Pseudomonas fluorescens	4-oxobutanoate + L-glutamate	-	r

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.6.1.19	pyridoxal 5'-phosphate	-	Rattus norvegicus
2.6.1.19	pyridoxal 5'-phosphate	-	Pseudomonas fluorescens

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Release 2023.1 (January 2023)