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Literature summary extracted from

  • Park, J.; Osei, Y.D.; Churchich, J.E.
    Isolation and characterization of recombinant mitochondrial 4-aminobutyrate aminotransferase (1993), J. Biol. Chem., 268, 7636-7639.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.19 brain cDNA, expressed in Escherichia coli strain BL21(DE3)pLysS transformed with expression vector pETG1.5 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.19 0.13 0.27 2-oxoglutarate
-
 Sus scrofa
2.6.1.19 1.1
-
 4-aminobutanoate
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.19 mitochondrion
-
 Sus scrofa 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.19 Sus scrofa
-
 expressed in Escherichia coli
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.19 expressed in E. coli Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.19 brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6.1.19 18.2
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.19 4-aminobutanoate + 2-oxoglutarate
-
 Sus scrofa 4-oxobutanoate + L-glutamate
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.19 pyridoxal 5'-phosphate
-
 Sus scrofa