Literature summary extracted from

Savarese, T.M.; Crabtree, G.W.; Parks, R.E.
5'-Methylthioadenosine phosphorylase. I. Substrate activity of 5'-deoxyadenosine with the enzyme from Sarcoma 180 cells (1981), Biochem. Pharmacol., 30, 189-199.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.2.28	5'-Deoxy-5'-chloroformycin	competitive	Mus musculus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.4.2.28	0.004	-	5'-deoxy-5'-methylthioadenosine	-	Mus musculus
2.4.2.28	3.5	-	phosphate	-	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.28	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.2.28	CCRF S-180 II cell	-	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.28	5'-deoxy-5'-methylthioadenosine + phosphate	-	Mus musculus	adenine + 5-methylthio-D-ribose 1-phosphate	-	r
2.4.2.28	5'-deoxyadenosine + phosphate	phosphate-dependent	Mus musculus	adenine + 5-deoxy-D-ribose 1-phosphate	-	r
2.4.2.28	5'-methylthioadenosine + phosphate	-	Mus musculus	adenine + 5-methylthio-D-ribose 1-phosphate	-	r

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Release 2023.1 (January 2023)