EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.2.8 | functional expression in Escherichia coli | Tritrichomonas suis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.8 | immucillin-H | transition state analogue, binds tightly to the active site, inhibition mechanism and kinetics | Tritrichomonas suis | |
2.4.2.8 | immucillin-H 5'-phosphate | transition state analogue, binds tightly to the active site, inhibition mechanism and kinetics | Tritrichomonas suis |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.8 | Mg2+ | required | Tritrichomonas suis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.8 | Tritrichomonas suis | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.8 | recombinant from Escherichia coli | Tritrichomonas suis |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.4.2.8 | IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | catalytic mechanism | Tritrichomonas suis | |
2.4.2.8 | IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | active site structure | Tritrichomonas suis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.8 | guanine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Tritrichomonas suis | GMP + diphosphate | - |
r | |
2.4.2.8 | hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Tritrichomonas suis | IMP + diphosphate | - |
r |