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Literature summary extracted from

  • Zolfaghari, R.; Wang, Y.; Chen, Q.; Sancher, A.; Ross, A.C.
    Cloning and molecular expression analysis of large and small lecithin:retinol acyltransferase mRNAs in the liver and other tissues of adult rats (2002), Biochem. J., 368, 621-631.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.135 additional information retinoic acid must be continuously present to maintain LRAT gene expression in the ON position Rattus norvegicus
2.3.1.135 additional information activation and mRNA expression for LRAT is blocked completely in vivo by actinomycin D Rattus norvegicus
2.3.1.135 retinoic acid minimal dose for significant increase in LRAT activity and mRNA expression: 0.005 mg Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.135 expression in HEK-293T cells Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.135 Rattus norvegicus Q9JI61
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.135 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.135 phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
 Rattus norvegicus 2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
 ?