EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.29 | Triton X-100 | stimulates farnesyl-transferring activity, inhibits dimethylallyl-transferring activity | Micrococcus luteus | |
2.5.1.29 | Tween 80 | stimulates | Micrococcus luteus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.29 | diphosphate | - |
Micrococcus luteus | |
2.5.1.29 | farnesyl diphosphate | - |
Micrococcus luteus | |
2.5.1.29 | Triton X-100 | stimulates farnesyl-transferring activity, inhibits dimethylallyl-transferring activity | Micrococcus luteus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.29 | Mg2+ | required for activity | Micrococcus luteus | |
2.5.1.29 | Mg2+ | optimal activation of farnesyl-transferring activity at 1 mM, optimal activation of dimethylallyl-transferring activity at 3 mM | Micrococcus luteus | |
2.5.1.29 | Mn2+ | slight activation | Micrococcus luteus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.5.1.29 | 70000 | - |
gel filtration | Micrococcus luteus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.29 | (E,E)-farnesyl diphosphate + isopentenyl diphosphate | Micrococcus luteus | - |
geranylgeranyl diphosphate + diphosphate | - |
? | |
2.5.1.29 | geranyl diphosphate + 2 isopentenyl diphosphate | Micrococcus luteus | - |
geranylgeranyl diphosphate + 2 diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.29 | Micrococcus luteus | - |
the activities of EC 2.5.1.1 and EC 2.5.1.29 may be a mixture of 2 enzymes or a single enzyme with two independent catalytic sites, see EC 2.5.1.1 | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.5.1.29 | - |
Micrococcus luteus |
EC Number | Storage Stability | Organism |
---|---|---|
2.5.1.29 | -20°C, at least 1 week, no loss of activity | Micrococcus luteus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.29 | (E)-3-methyl-2-dodecenyl diphosphate + isopentenyl diphosphate | 45% of the activity with farnesyl diphosphate | Micrococcus luteus | (2E,5E)-3,6-dimethylpentadeca-2,5-dien-1-yl diphosphate + diphosphate | - |
? | |
2.5.1.29 | (E,E)-farnesyl diphosphate + isopentenyl diphosphate | - |
Micrococcus luteus | geranylgeranyl diphosphate + diphosphate | - |
? | |
2.5.1.29 | E-3-methyl-2-undecenyl diphosphate + isopentenyl diphosphate | 53% of the activity with farnesyl diphosphate | Micrococcus luteus | ? | - |
? | |
2.5.1.29 | geranyl diphosphate + 2 isopentenyl diphosphate | - |
Micrococcus luteus | geranylgeranyl diphosphate + 2 diphosphate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.5.1.29 | 7.7 | - |
- |
Micrococcus luteus |