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Literature summary extracted from

  • Kikuchi, H.; Ikeda, Y.; Tsuiki, S.
    Inhibition of L-glutamine:D-fructose-6-phosphate aminotransferase by methylglyoxal (1972), Biochim. Biophys. Acta, 289, 303-310.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.16 dihydroxyacetone weak Rattus norvegicus
2.6.1.16 dihydroxyacetone phosphate weak Rattus norvegicus
2.6.1.16 fructose 1,6-diphosphate weak Rattus norvegicus
2.6.1.16 glyceraldehyde 3-phosphate 50% inhibition at 0.2 mM Rattus norvegicus
2.6.1.16 glycolaldehyde weak Rattus norvegicus
2.6.1.16 Glyoxal 50% inhibition at 0.03 mM Rattus norvegicus
2.6.1.16 L-alpha-glycerophosphate weak Rattus norvegicus
2.6.1.16 methylglyoxal 50% inhibition at 0.01 mM, non competitive Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.16 Rattus norvegicus
-
 rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.16 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.16 L-glutamine + D-fructose 6-phosphate
-
 Rattus norvegicus L-glutamate + D-glucosamine 6-phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.16 37
-
 assay at Rattus norvegicus