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Literature summary extracted from

  • Van Leuven, F.
    Glutamine transaminase from brain tissue. Further studies on kinetic properties and specificity of the enzyme (1976), Eur. J. Biochem., 65, 271-274.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.64 0.023
-
 phenylpyruvate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 0.092
-
 L-phenylalanine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 0.25
-
 2-oxo-4-methiolbutyrate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 0.61
-
 3-Mercaptopyruvate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 0.63
-
 L-glutamine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 1.46
-
 glyoxalate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 1.96
-
 L-methionine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 2.15
-
 L-methionine(SR)sulfoxide pH 7.0, 30°C Rattus norvegicus
2.6.1.64 2.53
-
 L-ethionine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 2.85
-
 L-S-methylcysteine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 6.76
-
 2-oxovalerate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 6.91
-
 L-5-N-Methylglutamine pH 7.0, 30°C Rattus norvegicus
2.6.1.64 9.19
-
 2-oxobutyrate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 13.5
-
 pyruvate pH 7.0, 30°C, L-glutamine as amino group donor Rattus norvegicus
2.6.1.64 16.5
-
 L-glutamate-5-methylester pH 7.0, 30°C Rattus norvegicus
2.6.1.64 20.5
-
 2-Oxoglutaramate pH 7.0, 30°C, L-phenylalanine as amino group donor Rattus norvegicus
2.6.1.64 96
-
 L-glutamate-5-ethylester pH 7.0, 30°C Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.64 L-glutamine + phenylpyruvate Rattus norvegicus
-
 2-oxoglutaramate + L-phenylalanine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.64 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.64
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.64 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.64 DL-methionine-SR-sulfoximine + phenylpyruvate
-
 Rattus norvegicus 4-methylsulfanyl-2-oxobutanoate-SR-sulfoximine + L-phenylalanine
-
 r
2.6.1.64 L-5-N-hydroxyglutamine + phenylpyruvate
-
 Rattus norvegicus 4-(N-hydroxycarbamoyl)-2-oxobutanoate + L-phenylalanine
-
 r
2.6.1.64 L-5-N-methylglutamine + glyoxylate
-
 Rattus norvegicus 4-(N-methylcarbamoyl)-2-oxobutanoate + glycine
-
 r
2.6.1.64 L-5-N-methylglutamine + phenylpyruvate
-
 Rattus norvegicus 4-(N-methylcarbamoyl)-2-oxobutanoate + L-phenylalanine
-
 r
2.6.1.64 L-asparagine + phenylpyruvate
-
 Rattus norvegicus 2-oxosuccinamate + L-phenylalanine
-
 r
2.6.1.64 L-cysteine + phenylpyruvate
-
 Rattus norvegicus 3-mercapto-2-oxopropanoate + L-phenylalanine
-
 r
2.6.1.64 L-ethionine + glyoxylate
-
 Rattus norvegicus 4-ethylsulfanyl-2-oxobutanoate + glycine
-
 r
2.6.1.64 L-ethionine + phenylpyruvate
-
 Rattus norvegicus 4-ethylsulfanyl-2-oxobutanoate + L-phenylalanine
-
 r
2.6.1.64 L-glutamate-5-ethylester + phenylpyruvate
-
 Rattus norvegicus 2-oxoglutarate-5-ethylester + L-phenylalanine
-
 r
2.6.1.64 L-glutamate-5-methylester + phenylpyruvate
-
 Rattus norvegicus 2-oxoglutarate-5-methylester + L-phenylalanine
-
 r
2.6.1.64 L-glutamine + 2-oxo-4-methiolbutyrate
-
 Rattus norvegicus 2-oxoglutaramate + L-methionine
-
 r
2.6.1.64 L-glutamine + 2-oxo-4-methyl valerate
-
 Rattus norvegicus 2-oxoglutaramate + L-4-methyl-norvaline
-
 r
2.6.1.64 L-glutamine + 2-oxobutyrate
-
 Rattus norvegicus 2-oxoglutaramate + 2-aminobutanoate
-
 r
2.6.1.64 L-glutamine + 2-oxoglutarate
-
 Rattus norvegicus 2-oxoglutaramate + L-glutamate
-
 r
2.6.1.64 L-glutamine + 2-oxoisovalerate
-
 Rattus norvegicus 2-oxoglutaramate + L-valine
-
 r
2.6.1.64 L-glutamine + 2-oxovalerate
-
 Rattus norvegicus 2-oxoglutaramate + L-norvaline
-
 r
2.6.1.64 L-glutamine + 3-bromopyruvate
-
 Rattus norvegicus 2-oxoglutaramate + 2-amino-3-bromopropionic acid
-
 r
2.6.1.64 L-glutamine + 3-hydroxypyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-serine
-
 r
2.6.1.64 L-glutamine + 3-indolepyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-tryptophan
-
 r
2.6.1.64 L-glutamine + 3-methyl-2-oxo-pentanoate
-
 Rattus norvegicus 2-oxoglutaramate + L-3-methyl-norvaline
-
 r
2.6.1.64 L-glutamine + 4-methylsulfanyl-2-oxobutanoate
-
 Rattus norvegicus 2-oxoglutaramate + L-methionine
-
 r
2.6.1.64 L-glutamine + glyoxylate
-
 Rattus norvegicus 2-oxoglutaramate + glycine
-
 r
2.6.1.64 L-glutamine + oxaloacetate
-
 Rattus norvegicus 2-oxoglutaramate + L-aspartate
-
 r
2.6.1.64 L-glutamine + p-hydroxyphenylpyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-tyrosine
-
 r
2.6.1.64 L-glutamine + phenylpyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-phenylalanine
-
 r
2.6.1.64 L-glutamine + pyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-alanine
-
 r
2.6.1.64 L-histidine + glyoxylate
-
 Rattus norvegicus 3-(1H-imidazol-4-yl)-2-oxopropanoate + glycine
-
 r
2.6.1.64 L-methionine + glyoxylate
-
 Rattus norvegicus 4-methylsulfanyl-2-oxobutanoate + glycine
-
 r
2.6.1.64 L-methionine + phenylpyruvate
-
 Rattus norvegicus 4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
-
 r
2.6.1.64 L-methionine-SR-sulfoxide + phenylpyruvate
-
 Rattus norvegicus 4-methylsulfinyl-2-oxobutanoate + L-phenylalanine
-
 r
2.6.1.64 L-phenylalanine + glyoxylate
-
 Rattus norvegicus phenylpyruvate + glycine
-
 r
2.6.1.64 L-tyrosine + glyoxylate
-
 Rattus norvegicus 3(4-hydroxyphenyl)-2-oxopropanoate + glycine
-
 r
2.6.1.64 additional information not active with L-glutamate, L-aspartate, L-cysteine, glycine, L-alanine, L-serine, L-proline, L-hydroxyproline, L-valine, L-leucine, L-isoleucine, L-threonine, L-lysine and 4-aminobutyrate Rattus norvegicus ?
-
 ?
2.6.1.64 S-methyl-L-cysteine + phenylpyruvate
-
 Rattus norvegicus 3-methylsulfanyl-2-oxopropanoate + L-phenylalanine
-
 r