EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.11 | ATP | above 1 mM, inhibition is relieved by Mg2+; free form | Solanum lycopersicum | |
2.7.1.11 | CTP | free form, Mg2+ relieves | Solanum lycopersicum | |
2.7.1.11 | GTP | free form, Mg2+ relieves | Solanum lycopersicum | |
2.7.1.11 | additional information | not inhibited by MgATP2- | Solanum lycopersicum | |
2.7.1.11 | UTP | free form, Mg2+ relieves | Solanum lycopersicum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.11 | additional information | - |
additional information | kinetic study | Solanum lycopersicum | |
2.7.1.11 | additional information | - |
additional information | oligomeric form exhibits negative cooperativity with fructose 6-phosphate | Solanum lycopersicum |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.11 | Mg2+ | required for activity | Solanum lycopersicum | |
2.7.1.11 | Mg2+ | maximal activity at 5 mM, Km-value: 0.84 mM | Solanum lycopersicum | |
2.7.1.11 | Mg2+ | MgATP is the active substrate | Solanum lycopersicum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.11 | ATP + D-fructose 6-phosphate | Solanum lycopersicum | allosteric enzyme, involved in regulation of glycolytic flux | ADP + D-fructose 1,6-bisphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.11 | Solanum lycopersicum | - |
tomato, var. Eurocross BB | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.11 | fruit | - |
Solanum lycopersicum | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.11 | ATP + D-fructose 6-phosphate | - |
Solanum lycopersicum | ADP + D-fructose 1,6-bisphosphate | - |
? | |
2.7.1.11 | ATP + D-fructose 6-phosphate | allosteric enzyme, involved in regulation of glycolytic flux | Solanum lycopersicum | ADP + D-fructose 1,6-bisphosphate | - |
? | |
2.7.1.11 | CTP + D-fructose 6-phosphate | less effective than ATP | Solanum lycopersicum | CDP + D-fructose 1,6-bisphosphate | - |
? | |
2.7.1.11 | GTP + D-fructose 6-phosphate | almost as effective as ATP | Solanum lycopersicum | GDP + D-fructose 1,6-bisphosphate | - |
? | |
2.7.1.11 | ITP + D-fructose 6-phosphate | less effective than ATP | Solanum lycopersicum | IDP + D-fructose 1,6-bisphosphate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.11 | 25 | - |
assay at | Solanum lycopersicum |