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Literature summary extracted from

  • Turnquist, R.L.; Hansen, R.G.
    Uridine diphosphoryl glucose pyrophosphorylase (1973), The Enzymes, 3rd. Ed. (Boyer, P. D. , ed. ), 8, 51-71.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.9 2-mercaptoethanol
-
 Bos taurus
2.7.7.9 2-mercaptoethanol
-
 Oryctolagus cuniculus
2.7.7.9 2-mercaptoethanol requirement Homo sapiens
2.7.7.9 DTT requirement Homo sapiens
2.7.7.9 additional information
-
 Bos taurus
2.7.7.9 additional information rat mammary gland enzyme seems to undergo structural changes that lead to a more active form Rattus norvegicus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.7.9 from ammonium sulfate precipitate Bos taurus
2.7.7.9 from ammonium sulfate precipitate Oryctolagus cuniculus
2.7.7.9 from ammonium sulfate precipitate Ovis aries
2.7.7.9 from ammonium sulfate precipitate Capra hircus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.9 alpha-D-galactose 1-phosphate at high concentrations Bos taurus
2.7.7.9 alpha-D-galactose 1-phosphate
-
 Oryctolagus cuniculus
2.7.7.9 D-galactosamine
-
 Bos taurus
2.7.7.9 diphosphate possible alternate regulatory mechanism; product inhibition Dictyostelium discoideum
2.7.7.9 diphosphate product inhibition Rattus norvegicus
2.7.7.9 additional information
-
 Acetabularia sp.
2.7.7.9 additional information
-
 Beta vulgaris subsp. vulgaris
2.7.7.9 additional information
-
 Bombyx mori
2.7.7.9 additional information
-
 Bos taurus
2.7.7.9 additional information
-
 Canis lupus familiaris
2.7.7.9 additional information
-
 Capra hircus
2.7.7.9 additional information
-
 Columba sp.
2.7.7.9 additional information
-
 Dictyostelium discoideum
2.7.7.9 additional information
-
 Escherichia coli
2.7.7.9 additional information
-
 Gallus gallus
2.7.7.9 additional information
-
 Homo sapiens
2.7.7.9 additional information
-
 Oryctolagus cuniculus
2.7.7.9 additional information
-
 Ovis aries
2.7.7.9 additional information
-
 Pisum sativum
2.7.7.9 additional information
-
 Rattus norvegicus
2.7.7.9 additional information
-
 Saccharomyces cerevisiae
2.7.7.9 additional information
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 additional information
-
 Zea mays
2.7.7.9 phosphate
-
 Bos taurus
2.7.7.9 TDP-glucose
-
 Escherichia coli
2.7.7.9 TDP-rhamnose
-
 Escherichia coli
2.7.7.9 UDP
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Escherichia coli
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Homo sapiens
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Rattus norvegicus
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Saccharomyces cerevisiae
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Bos taurus
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Oryctolagus cuniculus
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Dictyostelium discoideum
2.7.7.9 additional information
-
 additional information kinetic parameters of various organisms, pH 8.0, overview Canis lupus familiaris
2.7.7.9 0.048
-
 UTP
-
 Oryctolagus cuniculus
2.7.7.9 0.048
-
 UTP liver Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.9 amyloplast
-
 Pisum sativum 9501
-
2.7.7.9 amyloplast
-
 Zea mays 9501
-
2.7.7.9 chloroplast
-
 Pisum sativum 9507
-
2.7.7.9 chloroplast
-
 Zea mays 9507
-
2.7.7.9 chloroplast
-
 Beta vulgaris subsp. vulgaris 9507
-
2.7.7.9 chloroplast
-
 Acetabularia sp. 9507
-
2.7.7.9 cytosol
-
 Escherichia coli 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Gallus gallus 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Rattus norvegicus 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Bos taurus 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Bombyx mori 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Oryctolagus cuniculus 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Ovis aries 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Pisum sativum 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Zea mays 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Canis lupus familiaris 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Capra hircus 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Columba sp. 5829
-
2.7.7.9 cytosol predominantly, plant or animal cells Beta vulgaris subsp. vulgaris 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.9 Co2+ about 25% as effective as Mg2+ Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 Co2+ about 25% as effective as Mg2+ Gallus gallus
2.7.7.9 Co2+ about 25% as effective as Mg2+ Escherichia coli
2.7.7.9 Co2+ about 25% as effective as Mg2+ Homo sapiens
2.7.7.9 Co2+ about 25% as effective as Mg2+ Rattus norvegicus
2.7.7.9 Co2+ about 25% as effective as Mg2+ Saccharomyces cerevisiae
2.7.7.9 Co2+ about 25% as effective as Mg2+ Bos taurus
2.7.7.9 Co2+ about 25% as effective as Mg2+ Bombyx mori
2.7.7.9 Co2+ about 25% as effective as Mg2+ Oryctolagus cuniculus
2.7.7.9 Co2+ about 25% as effective as Mg2+ Ovis aries
2.7.7.9 Co2+ about 25% as effective as Mg2+ Pisum sativum
2.7.7.9 Co2+ about 25% as effective as Mg2+ Zea mays
2.7.7.9 Co2+ about 25% as effective as Mg2+ Dictyostelium discoideum
2.7.7.9 Co2+ about 25% as effective as Mg2+ Canis lupus familiaris
2.7.7.9 Co2+ about 25% as effective as Mg2+ Capra hircus
2.7.7.9 Co2+ about 25% as effective as Mg2+ Columba sp.
2.7.7.9 Co2+ about 25% as effective as Mg2+ Beta vulgaris subsp. vulgaris
2.7.7.9 Co2+ about 25% as effective as Mg2+ Acetabularia sp.
2.7.7.9 Mg2+ requirement Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 Mg2+ requirement Gallus gallus
2.7.7.9 Mg2+ requirement Escherichia coli
2.7.7.9 Mg2+ requirement Homo sapiens
2.7.7.9 Mg2+ requirement Rattus norvegicus
2.7.7.9 Mg2+ requirement Saccharomyces cerevisiae
2.7.7.9 Mg2+ requirement Bos taurus
2.7.7.9 Mg2+ requirement Bombyx mori
2.7.7.9 Mg2+ requirement Oryctolagus cuniculus
2.7.7.9 Mg2+ requirement Ovis aries
2.7.7.9 Mg2+ requirement Pisum sativum
2.7.7.9 Mg2+ requirement Zea mays
2.7.7.9 Mg2+ requirement Dictyostelium discoideum
2.7.7.9 Mg2+ requirement Canis lupus familiaris
2.7.7.9 Mg2+ requirement Capra hircus
2.7.7.9 Mg2+ requirement Columba sp.
2.7.7.9 Mg2+ requirement Beta vulgaris subsp. vulgaris
2.7.7.9 Mg2+ requirement Acetabularia sp.
2.7.7.9 Mn2+ activation Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 Mn2+ activation Gallus gallus
2.7.7.9 Mn2+ activation Escherichia coli
2.7.7.9 Mn2+ activation Homo sapiens
2.7.7.9 Mn2+ activation Rattus norvegicus
2.7.7.9 Mn2+ activation Saccharomyces cerevisiae
2.7.7.9 Mn2+ activation Bos taurus
2.7.7.9 Mn2+ activation Bombyx mori
2.7.7.9 Mn2+ activation Oryctolagus cuniculus
2.7.7.9 Mn2+ activation Ovis aries
2.7.7.9 Mn2+ activation Pisum sativum
2.7.7.9 Mn2+ activation Zea mays
2.7.7.9 Mn2+ activation Dictyostelium discoideum
2.7.7.9 Mn2+ activation Canis lupus familiaris
2.7.7.9 Mn2+ activation Capra hircus
2.7.7.9 Mn2+ activation Columba sp.
2.7.7.9 Mn2+ activation Beta vulgaris subsp. vulgaris
2.7.7.9 Mn2+ activation Acetabularia sp.
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Gallus gallus
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Escherichia coli
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Homo sapiens
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Rattus norvegicus
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Saccharomyces cerevisiae
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Bos taurus
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Bombyx mori
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Oryctolagus cuniculus
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Ovis aries
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Pisum sativum
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Zea mays
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Dictyostelium discoideum
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Canis lupus familiaris
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Capra hircus
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Columba sp.
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Beta vulgaris subsp. vulgaris
2.7.7.9 Mn2+ about 25% as effective as Mg2+ Acetabularia sp.
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Gallus gallus
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Escherichia coli
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Homo sapiens
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Rattus norvegicus
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Saccharomyces cerevisiae
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Bos taurus
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Bombyx mori
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Oryctolagus cuniculus
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Ovis aries
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Pisum sativum
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Zea mays
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Dictyostelium discoideum
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Canis lupus familiaris
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Capra hircus
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Columba sp.
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Beta vulgaris subsp. vulgaris
2.7.7.9 Ni2+ about 25% as effective as Mg2+ Acetabularia sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.9 60000
-
 8 * 60000, SDS-PAGE Bos taurus
2.7.7.9 390000
-
 two, non-interconvertible, forms: the second one is lighter and more labile Dictyostelium discoideum
2.7.7.9 450000
-
-
 Homo sapiens
2.7.7.9 450000
-
 mammary gland Rattus norvegicus
2.7.7.9 480000
-
 sucrose density gradient centrifugation Bos taurus
2.7.7.9 480000
-
 multimers of this 480000 MW species exist, ultracentrifugation studies Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Salmonella enterica subsp. enterica serovar Typhimurium
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Gallus gallus
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Escherichia coli
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Homo sapiens
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Rattus norvegicus
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Saccharomyces cerevisiae
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Bos taurus
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Bombyx mori
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Oryctolagus cuniculus
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Ovis aries
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Pisum sativum
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Zea mays
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Dictyostelium discoideum
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Canis lupus familiaris
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Capra hircus
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Columba sp.
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Beta vulgaris subsp. vulgaris
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate Acetabularia sp.
-
 diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.9 Acetabularia sp.
-
-
-
2.7.7.9 Beta vulgaris subsp. vulgaris
-
 sugar beet
-
2.7.7.9 Bombyx mori
-
-
-
2.7.7.9 Bos taurus
-
-
-
2.7.7.9 Canis lupus familiaris
-
-
-
2.7.7.9 Capra hircus
-
-
-
2.7.7.9 Columba sp.
-
 pigeon
-
2.7.7.9 Dictyostelium discoideum
-
-
-
2.7.7.9 Escherichia coli
-
-
-
2.7.7.9 Gallus gallus
-
-
-
2.7.7.9 Homo sapiens
-
-
-
2.7.7.9 Oryctolagus cuniculus
-
-
-
2.7.7.9 Ovis aries
-
 lamb
-
2.7.7.9 Pisum sativum
-
-
-
2.7.7.9 Rattus norvegicus
-
-
-
2.7.7.9 Saccharomyces cerevisiae
-
-
-
2.7.7.9 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
2.7.7.9 Zea mays
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.9
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9
-
 Saccharomyces cerevisiae
2.7.7.9
-
 Zea mays
2.7.7.9
-
 Dictyostelium discoideum
2.7.7.9 from liver Homo sapiens
2.7.7.9 from liver Bos taurus
2.7.7.9 from liver Oryctolagus cuniculus
2.7.7.9 from liver Ovis aries
2.7.7.9 from liver Capra hircus
2.7.7.9 partial Rattus norvegicus

Reaction

EC Number Reaction Comment Organism Reaction ID
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Salmonella enterica subsp. enterica serovar Typhimurium
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Gallus gallus
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Escherichia coli
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Homo sapiens
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Rattus norvegicus
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Saccharomyces cerevisiae
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Bos taurus
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Bombyx mori
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Oryctolagus cuniculus
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Ovis aries
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Pisum sativum
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Zea mays
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Dictyostelium discoideum
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Canis lupus familiaris
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Capra hircus
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Columba sp.
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Beta vulgaris subsp. vulgaris
a
2.7.7.9 UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose mechanism Acetabularia sp.
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.9 adipose tissue
-
 Rattus norvegicus
-
2.7.7.9 brain
-
 Homo sapiens
-
2.7.7.9 erythrocyte
-
 Homo sapiens
-
2.7.7.9 heart
-
 Canis lupus familiaris
-
2.7.7.9 liver
-
 Homo sapiens
-
2.7.7.9 liver
-
 Rattus norvegicus
-
2.7.7.9 liver
-
 Bos taurus
-
2.7.7.9 liver
-
 Oryctolagus cuniculus
-
2.7.7.9 liver
-
 Ovis aries
-
2.7.7.9 liver
-
 Capra hircus
-
2.7.7.9 mammary gland
-
 Salmonella enterica subsp. enterica serovar Typhimurium
-
2.7.7.9 mammary gland
-
 Gallus gallus
-
2.7.7.9 mammary gland
-
 Escherichia coli
-
2.7.7.9 mammary gland
-
 Homo sapiens
-
2.7.7.9 mammary gland
-
 Rattus norvegicus
-
2.7.7.9 mammary gland
-
 Bos taurus
-
2.7.7.9 mammary gland
-
 Bombyx mori
-
2.7.7.9 mammary gland
-
 Oryctolagus cuniculus
-
2.7.7.9 mammary gland
-
 Ovis aries
-
2.7.7.9 mammary gland
-
 Dictyostelium discoideum
-
2.7.7.9 mammary gland
-
 Canis lupus familiaris
-
2.7.7.9 mammary gland
-
 Capra hircus
-
2.7.7.9 mammary gland
-
 Columba sp.
-
2.7.7.9 mammary gland
-
 Beta vulgaris subsp. vulgaris
-
2.7.7.9 mammary gland
-
 Acetabularia sp.
-
2.7.7.9 additional information tissue distribution Salmonella enterica subsp. enterica serovar Typhimurium
-
2.7.7.9 additional information tissue distribution Gallus gallus
-
2.7.7.9 additional information tissue distribution Escherichia coli
-
2.7.7.9 additional information tissue distribution Homo sapiens
-
2.7.7.9 additional information tissue distribution Rattus norvegicus
-
2.7.7.9 additional information tissue distribution Saccharomyces cerevisiae
-
2.7.7.9 additional information tissue distribution Bos taurus
-
2.7.7.9 additional information tissue distribution Bombyx mori
-
2.7.7.9 additional information tissue distribution Oryctolagus cuniculus
-
2.7.7.9 additional information tissue distribution Ovis aries
-
2.7.7.9 additional information tissue distribution Pisum sativum
-
2.7.7.9 additional information tissue distribution Zea mays
-
2.7.7.9 additional information tissue distribution Dictyostelium discoideum
-
2.7.7.9 additional information tissue distribution Canis lupus familiaris
-
2.7.7.9 additional information tissue distribution Capra hircus
-
2.7.7.9 additional information tissue distribution Columba sp.
-
2.7.7.9 additional information tissue distribution Beta vulgaris subsp. vulgaris
-
2.7.7.9 additional information tissue distribution Acetabularia sp.
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Salmonella enterica subsp. enterica serovar Typhimurium
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Gallus gallus
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Escherichia coli
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Homo sapiens
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Rattus norvegicus
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Saccharomyces cerevisiae
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Bos taurus
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Bombyx mori
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Oryctolagus cuniculus
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Ovis aries
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Pisum sativum
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Zea mays
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Dictyostelium discoideum
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Canis lupus familiaris
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Capra hircus
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Columba sp.
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Beta vulgaris subsp. vulgaris
-
2.7.7.9 additional information most abundant in tissues which display active polysaccharide synthesis Acetabularia sp.
-
2.7.7.9 muscle
-
 Rattus norvegicus
-
2.7.7.9 muscle
-
 Oryctolagus cuniculus
-
2.7.7.9 ovary
-
 Bombyx mori
-

Storage Stability

EC Number Storage Stability Organism
2.7.7.9 0°C, unstable upon storage Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.9 diphosphate + CDP-glucose calf and human liver, poor substrate Homo sapiens CTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + CDP-glucose calf and human liver, poor substrate Bos taurus CTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + GDP-glucose calf and human liver, poor substrate Homo sapiens GTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + GDP-glucose calf and human liver, poor substrate Bos taurus GTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + TDP-glucose poor substrate Homo sapiens TTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + TDP-glucose poor substrate Bos taurus TTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + TDP-glucose poor substrate Oryctolagus cuniculus TTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + TDP-glucose calf and human liver Homo sapiens TTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + TDP-glucose calf and human liver Bos taurus TTP + alpha-D-glucose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-mannose calf and human liver, poor substrate Homo sapiens UTP + D-mannose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-mannose calf and human liver, poor substrate Bos taurus UTP + D-mannose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose poor substrate Homo sapiens UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose poor substrate Bos taurus UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose poor substrate Oryctolagus cuniculus UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose calf and human liver Homo sapiens UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose calf and human liver Bos taurus UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 diphosphate + UDP-xylose calf and human liver Oryctolagus cuniculus UTP + D-xylose 1-phosphate
-
 r
2.7.7.9 UTP + alpha-D-galactose 1-phosphate
-
 Saccharomyces cerevisiae diphosphate + UDP-galactose
-
 r
2.7.7.9 UTP + alpha-D-galactose 1-phosphate
-
 Oryctolagus cuniculus diphosphate + UDP-galactose
-
 r
2.7.7.9 UTP + alpha-D-galactose 1-phosphate reverse reaction: calf and human liver Homo sapiens diphosphate + UDP-galactose
-
 r
2.7.7.9 UTP + alpha-D-galactose 1-phosphate reverse reaction: calf and human liver Bos taurus diphosphate + UDP-galactose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Gallus gallus diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Escherichia coli diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Homo sapiens diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Rattus norvegicus diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Saccharomyces cerevisiae diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Bos taurus diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Bombyx mori diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Oryctolagus cuniculus diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Ovis aries diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Pisum sativum diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Zea mays diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Dictyostelium discoideum diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Canis lupus familiaris diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Capra hircus diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Columba sp. diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Beta vulgaris subsp. vulgaris diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Acetabularia sp. diphosphate + UDP-glucose
-
 r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Gallus gallus diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Escherichia coli diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Homo sapiens diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Rattus norvegicus diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Saccharomyces cerevisiae diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Bos taurus diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Bombyx mori diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Oryctolagus cuniculus diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Ovis aries diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Pisum sativum diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Zea mays diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Dictyostelium discoideum diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Canis lupus familiaris diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Capra hircus diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Columba sp. diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Beta vulgaris subsp. vulgaris diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r
2.7.7.9 UTP + alpha-D-glucose 1-phosphate
-
 Acetabularia sp. diphosphate + UDP-glucose activation of glucosyl residues for glycogen synthesis, participates in synthesis of numerous compounds including cell wall polymers in higher plants and microorganisms, starch, trehalose, glycosides, glycolipids, heparin, microbial antigens, lactose, glucuronides, and rhamnose r

Subunits

EC Number Subunits Comment Organism
2.7.7.9 octamer
-
 Homo sapiens
2.7.7.9 octamer
-
 Oryctolagus cuniculus
2.7.7.9 octamer 8 * 60000, SDS-PAGE Bos taurus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.7.7.9 additional information
-
 isozymes of different heat stability Salmonella enterica subsp. enterica serovar Typhimurium

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.7.9 additional information
-
 additional information
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 additional information
-
 additional information
-
 Gallus gallus
2.7.7.9 additional information
-
 additional information
-
 Escherichia coli
2.7.7.9 additional information
-
 additional information
-
 Homo sapiens
2.7.7.9 additional information
-
 additional information
-
 Rattus norvegicus
2.7.7.9 additional information
-
 additional information
-
 Saccharomyces cerevisiae
2.7.7.9 additional information
-
 additional information
-
 Bos taurus
2.7.7.9 additional information
-
 additional information
-
 Bombyx mori
2.7.7.9 additional information
-
 additional information
-
 Oryctolagus cuniculus
2.7.7.9 additional information
-
 additional information
-
 Ovis aries
2.7.7.9 additional information
-
 additional information
-
 Pisum sativum
2.7.7.9 additional information
-
 additional information
-
 Zea mays
2.7.7.9 additional information
-
 additional information
-
 Dictyostelium discoideum
2.7.7.9 additional information
-
 additional information
-
 Canis lupus familiaris
2.7.7.9 additional information
-
 additional information
-
 Capra hircus
2.7.7.9 additional information
-
 additional information
-
 Columba sp.
2.7.7.9 additional information
-
 additional information
-
 Beta vulgaris subsp. vulgaris
2.7.7.9 additional information
-
 additional information
-
 Acetabularia sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.9 additional information
-
-
 Escherichia coli
2.7.7.9 additional information
-
-
 Oryctolagus cuniculus
2.7.7.9 additional information
-
 isozymes with different pH-optima Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 6.5 8
-
 Saccharomyces cerevisiae
2.7.7.9 6.5 8
-
 Oryctolagus cuniculus
2.7.7.9 7.5 9
-
 Escherichia coli
2.7.7.9 7.5 9
-
 Rattus norvegicus
2.7.7.9 7.5 9
-
 Pisum sativum
2.7.7.9 7.6 9.2 broad Homo sapiens
2.7.7.9 7.8
-
-
 Escherichia coli
2.7.7.9 7.8
-
-
 Dictyostelium discoideum
2.7.7.9 8 9 bovine mammary gland, human erythrocytes Homo sapiens
2.7.7.9 8 9 bovine mammary gland, human erythrocytes Bos taurus
2.7.7.9 8.5
-
-
 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Gallus gallus
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Escherichia coli
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Homo sapiens
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Rattus norvegicus
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Saccharomyces cerevisiae
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Bos taurus
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Bombyx mori
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Oryctolagus cuniculus
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Ovis aries
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Pisum sativum
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Zea mays
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Dictyostelium discoideum
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Canis lupus familiaris
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Capra hircus
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Columba sp.
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Beta vulgaris subsp. vulgaris
2.7.7.9 additional information
-
 additional information inhibition constants of various organisms Acetabularia sp.