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Literature summary extracted from

  • Masullp, M.; De Vendittis, E.; Bocchini, V.
    Archaebacterial elongation factor 1 alpha carries the catalytic site for GTP hydrolysis (1994), J. Biol. Chem., 269, 20376-20379.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.6.5.3 medicine polypeptide chain synthesis Saccharolobus solfataricus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.5.3 GDP
-
 Saccharolobus solfataricus
3.6.5.3 ITP
-
 Saccharolobus solfataricus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.5.3 0.002 0.009 GTP depending on NaCl-concentration and temperature Saccharolobus solfataricus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.5.3 Ba2+
-
 Saccharolobus solfataricus
3.6.5.3 Mg2+
-
 Saccharolobus solfataricus
3.6.5.3 Mn2+
-
 Saccharolobus solfataricus
3.6.5.3 Na+
-
 Saccharolobus solfataricus

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.3 Saccharolobus solfataricus
-
 strain ATCC 49255, elongation factor aEF-1alpha
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.3 GTP + H2O
-
 Saccharolobus solfataricus GDP + phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.5.3 87
-
-
 Saccharolobus solfataricus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
3.6.5.3 60 93
-
 Saccharolobus solfataricus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.5.3 5.5 10.5
-
 Saccharolobus solfataricus