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Literature summary extracted from
- Distribution of xanthine dehydrogenase and oxidase activities in human and rabbit tissues (1988), Biochem. Soc. Trans., 16, 358-359.
No PubMed abstract available
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.1.4 | xanthine + NAD+ + H2O | Homo sapiens | - |
urate + NADH | - |
r |  |
| 1.17.1.4 | xanthine + NAD+ + H2O | Oryctolagus cuniculus | - |
urate + NADH | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.17.1.4 | Homo sapiens | - |
- |
- |
| 1.17.1.4 | Oryctolagus cuniculus | - |
rabbit | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.17.1.4 | adrenal gland | - |
Homo sapiens | - |
| 1.17.1.4 | cerebellum | - |
Oryctolagus cuniculus | - |
| 1.17.1.4 | cerebellum | high rate of dehydrogenase activity | Homo sapiens | - |
| 1.17.1.4 | cerebral cortex | - |
Oryctolagus cuniculus | - |
| 1.17.1.4 | cerebral cortex | high rate of dehydrogenase activity | Homo sapiens | - |
| 1.17.1.4 | heart | - |
Oryctolagus cuniculus | - |
| 1.17.1.4 | heart | high rate of dehydrogenase activity | Homo sapiens | - |
| 1.17.1.4 | kidney | - |
Homo sapiens | - |
| 1.17.1.4 | liver | high oxidase and reductase activities at nearly the same rates | Homo sapiens | - |
| 1.17.1.4 | liver | high oxidase and reductase activities at nearly the same rates | Oryctolagus cuniculus | - |
| 1.17.1.4 | placenta | very low oxidase and dehydrogenase activities | Homo sapiens | - |
| 1.17.1.4 | pons | - |
Oryctolagus cuniculus | - |
| 1.17.1.4 | pons | high rate of dehydrogenase activity | Homo sapiens | - |
| 1.17.1.4 | skeletal muscle | low oxidase activity | Homo sapiens | - |
| 1.17.1.4 | spleen | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.1.4 | xanthine + NAD+ + H2O | - |
Homo sapiens | urate + NADH | - |
r | |
| 1.17.1.4 | xanthine + NAD+ + H2O | - |
Oryctolagus cuniculus | urate + NADH | - |
r | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.17.1.4 | NAD+ | - |
Homo sapiens | |
| 1.17.1.4 | NAD+ | - |
Oryctolagus cuniculus | |
| 1.17.1.4 | NADH | - |
Homo sapiens | |
| 1.17.1.4 | NADH | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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