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Literature summary extracted from

  • Fhaolain, I.N.; Coughlan, M.P.
    Effects of limited proteolysis on the structure and activity of turkey liver xanthine dehydrogenase (1977), Biochem. Soc. Trans., 5, 1705-1707.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.1.4 Fe iron-sulfur groups Meleagris gallopavo
1.17.1.4 Mo
-
 Meleagris gallopavo

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.1.4 hypoxanthine + NAD+ + H+ + O2- + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa xanthine + NADH + H2O2
-
 ?
1.17.1.4 xanthine + NAD+ + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa urate + NADH
-
 ?
1.17.1.4 xanthine + O2 + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa urate + O2- + 2 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.1.4 Meleagris gallopavo
-
 turkey
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.1.4 liver
-
 Meleagris gallopavo
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.1.4 hypoxanthine + NAD+ + H+ + O2- + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo xanthine + NADH + H2O2
-
 ?
1.17.1.4 NADH + electron acceptor + H2O subtilisin treatment leads to an active component of 120000 kDa with enhanced activity Meleagris gallopavo NAD+ + reduced electron acceptor
-
 ?
1.17.1.4 NADH + electron acceptor + H2O NADH diaphorase activity with several acceptors Meleagris gallopavo NAD+ + reduced electron acceptor
-
 ?
1.17.1.4 xanthine + 2,6-dichlorophenolindophenol + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + ?
-
 ?
1.17.1.4 xanthine + methylene blue + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + reduced methylene blue
-
 ?
1.17.1.4 xanthine + NAD+ + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo urate + NADH
-
 ?
1.17.1.4 xanthine + O2 + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo urate + O2- + 2 H+
-
 ?
1.17.1.4 xanthine + trinitrobenzenesulfonate + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + ?
-
 ?

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.17.1.4 11
-
 no effect on activity Meleagris gallopavo

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.1.4 FAD
-
 Meleagris gallopavo
1.17.1.4 NAD+
-
 Meleagris gallopavo