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Literature summary extracted from

  • Michaels, G.; Milner, Y.; Moskovitz, B.R.; Wood, H.G.
    Pyruvate, phosphate dikinase. Metal cation requirements and inactivation of the enzyme by sulfhydryl agents (1978), J. Biol. Chem., 253, 7656-7661.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.7.9.1 slowly inactivates when kept at 4ºC [Clostridium] symbiosum

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.9.1 5,5-dithiobis(2-nitrobenzoic acid)
-
 [Clostridium] symbiosum
2.7.9.1 Co2+ at high concentration inhibits the phosphoenolpyruvate, pyruvate exchange reaction [Clostridium] symbiosum
2.7.9.1 Mn2+ at high concentration inhibits the phosphate, diphosphate exchange reaction [Clostridium] symbiosum
2.7.9.1 additional information not inhibited by iodoacetamide [Clostridium] symbiosum
2.7.9.1 N-ethylmaleimide
-
 [Clostridium] symbiosum
2.7.9.1 p-hydroxymercuribenzoate
-
 [Clostridium] symbiosum
2.7.9.1 Sulfhydryl agents
-
 [Clostridium] symbiosum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.9.1 Co2+
-
 [Clostridium] symbiosum
2.7.9.1 K+
-
 [Clostridium] symbiosum
2.7.9.1 Mg2+
-
 [Clostridium] symbiosum
2.7.9.1 Mn2+
-
 [Clostridium] symbiosum
2.7.9.1 NH4+
-
 [Clostridium] symbiosum

Organism

EC Number Organism UniProt Comment Textmining
2.7.9.1 [Clostridium] symbiosum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.9.1 ATP + pyruvate + phosphate
-
 [Clostridium] symbiosum AMP + phosphoenolpyruvate + diphosphate
-
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