Literature summary extracted from
Morey, M.; Serras, F.; Corominas, M.
Halving the selenophosphate synthetase gene dose confers hypersensitivity to oxidative stress in Drosophila melanogaster (2003), FEBS Lett., 534, 111-114.
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
2.7.9.3 |
overexpression of the wild-type enzyme in motoneurons does not extend longevity |
Drosophila melanogaster |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
2.7.9.3 |
additional information |
selD mutant SelDptuf is less resistant to reactive oxygen species, paraquat and H2O2, compared to the wild-type |
Drosophila melanogaster |
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
2.7.9.3 |
ATP + selenide + H2O |
Drosophila melanogaster |
involved in synthesis of selenoproteins, that provide protection against oxidative stress by acting as cellular antioxidants |
AMP + selenophosphate + phosphate |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.7.9.3 |
Drosophila melanogaster |
- |
gene selD |
- |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
2.7.9.3 |
ATP + selenide + H2O |
involved in synthesis of selenoproteins, that provide protection against oxidative stress by acting as cellular antioxidants |
Drosophila melanogaster |
AMP + selenophosphate + phosphate |
- |
? |
|