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Literature summary extracted from
- Rhodanese as a thioredoxin oxidase (2000), Int. J. Biochem. Cell Biol., 32, 465-473.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 2.8.1.1 | expression in Escherichia coli | Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.8.1.1 | H2O2 | the less negative isoform is more instable to H2O2 | Bos taurus |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.8.1.1 | mitochondrion | two isoforms: a negative and a less negative form of rhodanese | Bos taurus | 5739 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.8.1.1 | thiosulfate + cyanide | Bos taurus | - |
sulfite + thiocyanate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.8.1.1 | Bos taurus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.8.1.1 | liver | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.8.1.1 | reduced thioredoxin + methane thiosulfonate | only the less negative rhodanese isoform catalyzes the oxidation of thioredoxin | Bos taurus | ? | - |
r | |
| 2.8.1.1 | thiosulfate + cyanide | - |
Bos taurus | sulfite + thiocyanate | - |
? | |
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Release 2023.1 (January 2023)
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