Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Prasannan, P.; Pike, S.; Peng, K.; Shane, B.; Appling, D.R.
    Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls (2003), J. Biol. Chem., 278, 43178-43187.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.4.3 expression in CHO cells and Saccharomyces cerevisiae Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.4.3 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.3 ATP + formate + tetrahydrofolate Homo sapiens
-
 ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.3 Homo sapiens Q6UB35
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.3 brain high transcript levels Homo sapiens
-
6.3.4.3 liver low transcript levels Homo sapiens
-
6.3.4.3 placenta high transcript levels Homo sapiens
-
6.3.4.3 skeletal muscle low transcript levels Homo sapiens
-
6.3.4.3 thymus high transcript levels Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.3 ATP + formate + tetrahydrofolate
-
 Homo sapiens ADP + phosphate + 10-formyltetrahydrofolate
-
 ?
6.3.4.3 ATP + formate + tetrahydrofolate trifuntional enzyme having 10-formyl-tetrahydrofolate synthetase, 5,10-methylene-tetrahydrofolate cyclohydrolase and 5,10-methylene-tetrahydrofolate dehydrogenase activity Homo sapiens ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.3 C1-tetrahydrofolate synthase
-
 Homo sapiens