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Literature summary extracted from
- Novel site in lipoprotein lipase (LPL415-438) essential for substrate interaction and dimer stability (2001), J. Lipid Res., 42, 1180-1186.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.1.34 | expression in HEK 293 cells | Homo sapiens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.34 | 55000 | - |
2 * 55000, dissociation of the dimer into monomers leads to irreversible loss of activity | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.34 | triacylglycerol + H2O | Homo sapiens | - |
diacylglycerol + a carboxylate | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.34 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | glycoprotein | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.34 | adipocyte | - |
Homo sapiens | - |
| 3.1.1.34 | macrophage | - |
Homo sapiens | - |
| 3.1.1.34 | muscle | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.34 | 1.7 | - |
substrate tributyrin | Homo sapiens |
| 3.1.1.34 | 39.2 | - |
substrate triolein | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.34 | triacylglycerol + H2O | - |
Homo sapiens | diacylglycerol + a carboxylate | - |
? | |
| 3.1.1.34 | tributyrin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.1.1.34 | triolein + H2O | - |
Homo sapiens | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | dimer | 2 * 55000, dissociation of the dimer into monomers leads to irreversible loss of activity | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | LPL | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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