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Literature summary extracted from
- Phenylacetyl coenzyme A hydrolase (1975), Methods Enzymol., 43, 482-487.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.2.25 | additional information | sensitive to SH group inhibitors | Penicillium chrysogenum |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.2.25 | 3.95 | - |
phenylacetyl-CoA | - |
Penicillium chrysogenum |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.25 | 25000 | - |
gel filtration | Penicillium chrysogenum |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.2.25 | Penicillium chrysogenum | - |
- |
- |
Oxidation Stability
| EC Number | Oxidation Stability | Organism |
|---|---|---|
| 3.1.2.25 | thiols are necessary during purification to prevent oxidation | Penicillium chrysogenum |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.2.25 | 130fold | Penicillium chrysogenum |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.25 | p-nitrophenyl acetate + H2O | hydrolyzes p-nitrophenyl acetate at the same rate as phenylacetyl-CoA or phenoxyacetylglycine | Penicillium chrysogenum | p-nitrophenol + acetate | - |
? | |
| 3.1.2.25 | phenoxyacetyl-CoA + H2O | approximately 5fold higher activity than with phenylacetyl-CoA | Penicillium chrysogenum | phenoxyacetate + CoA | - |
? | |
| 3.1.2.25 | phenoxyacetylglycine + H2O | hydrolyzes phenoxyacetylglycine at the same rate as phenylacetyl-CoA or p-nitrophenyl acetate | Penicillium chrysogenum | ? | - |
? | |
| 3.1.2.25 | phenylacetyl-CoA + H2O | hydrolyzes phenylacetyl-CoA at the same rate as p-nitrophenyl acetate or phenoxyacetylglycine, approximately 5fold lower activity as with phenoxyacetyl-CoA | Penicillium chrysogenum | phenylacetate + CoA | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.2.25 | phenylacetyl coenzyme A hydrolase | - |
Penicillium chrysogenum |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.25 | 7.6 | 7.8 | - |
Penicillium chrysogenum |
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Release 2023.1 (January 2023)
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