Literature summary extracted from

McCormick, S.J.; Tunnicliff, G.
Kinetics of inactivation of glutamate decarboxylase by cysteine-specific reagents (2001), Acta Biochim. Pol., 48, 573-578.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.1.1.15	5,5'-dithiobis(2-nitrobenzoate)	0.1 mM, 50.3% inhibition at pH 4.6, irreversible	Escherichia coli
4.1.1.15	Chloroacetamide	no inhibition at pH 4.6, marked inhibition at pH 6.0 or higher	Escherichia coli
4.1.1.15	HgCl2	0.01 mM, 80.1% inhibition at pH 4.6, irreversible	Escherichia coli
4.1.1.15	NEM	no inhibition at pH 4.6, marked inhibition at pH 6.0 or higher	Escherichia coli
4.1.1.15	PCMB	0.1 mM, 68.5% inhibition at pH 4.6, irreversible	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.15	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.15	L-Glu	-	Escherichia coli	4-Aminobutanoate + CO2	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
4.1.1.15	4	5	-	Escherichia coli

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Release 2023.1 (January 2023)