Literature summary extracted from
Esposito, L.; Bruno, I.; Sica, F.; Raia, C.A.; Giordano, A.; Rossi, M.; Mazzarella, L.; Zagari, A.
Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus (2003), Biochemistry, 42, 14397-14407.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
1.1.1.1 |
apoenzyme and ternary complex of enzyme with NADH and 2-ethoxyethanol bound to each subunit, X-ray diffraction structure determination and analysis at 2.3 A resolution |
Saccharolobus solfataricus |
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
1.1.1.1 |
Zn2+ |
the catalytic active site zinc ion is bound to Glu69 in the apoenzyme state, but not in the ternary complex state |
Saccharolobus solfataricus |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
1.1.1.1 |
Saccharolobus solfataricus |
P39462 |
- |
- |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
1.1.1.1 |
additional information |
the enzyme undergoes a substantial conformational change in the apo-holo transition, accompanied by loop movements at the domain interface |
Saccharolobus solfataricus |
? |
- |
? |
|
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
1.1.1.1 |
ADH |
- |
Saccharolobus solfataricus |