Literature summary extracted from
Whitby, F.G.; Phillips, J.D.; Hill, C.P.; McCoubrey, W.; Maines, M.D.
Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex (2002), J. Mol. Biol., 319, 1199-1210.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
1.3.1.24 |
apo enzyme and in complex with NADH |
Rattus norvegicus |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
1.3.1.24 |
Y97F |
50% of activity compared to wild type |
Rattus norvegicus |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
1.3.1.24 |
Rattus norvegicus |
P46844 |
- |
- |
Reaction
EC Number |
Reaction |
Comment |
Organism |
Reaction ID |
---|
1.3.1.24 |
bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+ |
catalysis via hydride transfer from NADH |
Rattus norvegicus |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
1.3.1.24 |
More |
general acid in catalysis is Y97 |
Rattus norvegicus |
Cofactor
EC Number |
Cofactor |
Comment |
Organism |
Structure |
---|
1.3.1.24 |
NADH |
- |
Rattus norvegicus |
|