EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.7.2.5 | cytochrome c | - |
Schinkia azotoformans | |
1.7.5.2 | cytochrome c551 | noncompetitive inhibitor of nitric oxide reduction when menaquinol is used as an electron donor | Schinkia azotoformans |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.7.2.5 | 0.14 | - |
5-hydroxy-1,4-naphthoquinone | - |
Schinkia azotoformans | |
1.7.2.5 | 0.26 | - |
5-hydroxy-2-methyl-1,4-naphthoquinol | - |
Schinkia azotoformans | |
1.7.5.2 | 0.0045 | - |
cytochrome c551 | pH and temperature not specified in the publication | Schinkia azotoformans | |
1.7.5.2 | 0.141 | - |
juglone | pH and temperature not specified in the publication | Schinkia azotoformans | |
1.7.5.2 | 0.256 | - |
Plumbagin | pH and temperature not specified in the publication | Schinkia azotoformans |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.7.2.5 | copper | contains CuA in the small subunit | Schinkia azotoformans | |
1.7.5.2 | copper | the enzyme contains a CuA center in its small subunit | Schinkia azotoformans |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.7.2.5 | NO + reduced acceptor | Schinkia azotoformans | - |
N2O + H2O + acceptor | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.7.2.5 | Schinkia azotoformans | - |
- |
- |
1.7.5.2 | Schinkia azotoformans | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.7.2.5 | NO + 5-hydroxy-1,4-naphthoquinol | - |
Schinkia azotoformans | N2O + H2O + 5-hydroxy-1,4-naphthoquinone | - |
? | |
1.7.2.5 | NO + 5-hydroxy-2-methyl-1,4-naphthoquinol | - |
Schinkia azotoformans | N2O + H2O + 5-hydroxy-2-methyl-1,4-naphthoquinone | - |
? | |
1.7.2.5 | NO + menaquinol | - |
Schinkia azotoformans | N2O + H2O + menaquinone | - |
? | |
1.7.2.5 | NO + reduced acceptor | - |
Schinkia azotoformans | N2O + H2O + acceptor | - |
? | |
1.7.2.5 | NO + reduced cytochrome c551 | - |
Schinkia azotoformans | N2O + H2O + oxidized cytochrome c551 | - |
? | |
1.7.5.2 | additional information | no activity with lapachol, reduced horse heart cytochrome c, cytochrome c550, and cytochrome c552 | Schinkia azotoformans | ? | - |
? | |
1.7.5.2 | nitric oxide + cytochrome c551 | the menaquinol pathway has a 4fold greater maximal activity than the pathway via cytochrome c551 | Schinkia azotoformans | ? | - |
? | |
1.7.5.2 | nitric oxide + juglone | - |
Schinkia azotoformans | ? | - |
? | |
1.7.5.2 | nitric oxide + menaquinol | the menaquinol pathway has a 4fold greater maximal activity than the pathway via cytochrome c551 | Schinkia azotoformans | nitrous oxide + menaquinone + H2O | - |
? | |
1.7.5.2 | nitric oxide + plumbagin | - |
Schinkia azotoformans | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.7.2.5 | qCuANOR | - |
Schinkia azotoformans |
1.7.5.2 | menaquinol-dependent nitric oxide reductase | - |
Schinkia azotoformans |
1.7.5.2 | NO reductase | - |
Schinkia azotoformans |
1.7.5.2 | qCuANOR | - |
Schinkia azotoformans |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.7.2.5 | 118 | - |
NO | with 5-hydroxy-1,4-naphthoquinol | Schinkia azotoformans | |
1.7.2.5 | 150 | - |
NO | with 5-hydroxy-2-methyl-1,4-naphthoquinol | Schinkia azotoformans | |
1.7.5.2 | 41 | - |
nitric oxide | using cytochrome c551 as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
1.7.5.2 | 118 | - |
nitric oxide | using juglone as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
1.7.5.2 | 150 | - |
nitric oxide | using plumbagin as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
1.7.5.2 | 153 | - |
nitric oxide | using menaquinol as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.7.2.5 | 0.005 | - |
cytochrome c | - |
Schinkia azotoformans |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.7.5.2 | physiological function | the ability of qCuANOR to accept electrons from both menaquinol and cytochrome c551 may be related to the regulation of the rate of NO reduction especially as a defense mechanism of B. azotoformans against the toxicity of NO. The menaquinol pathway, which has a 4-fold greater maximal activity than the pathway via cytochrome c551, is used for NO detoxification, whereas electron donation via the endogenous cytochrome c involves the cytochrome b6f complex serving the bioenergetic needs of the organism | Schinkia azotoformans |