BRENDA - Enzyme Database show

Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle

Virkel, G.; Lifschitz, A.; Sallovitz, J.; Pis, A.; Lanusse, C.; Drug Metab. Dispos. 32, 536-544 (2004)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.13.32
microsome
-
Bos taurus
-
-
1.14.13.32
microsome
-
Ovis aries
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.14.13.32
Bos taurus
-
-
-
1.14.13.32
Ovis aries
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.13.32
liver
-
Bos taurus
-
1.14.13.32
liver
-
Ovis aries
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.13.32
albendazole + NADPH + O2
-
658526
Bos taurus
(+)-albendazole S-oxide + NADP+
100% enantioselective towards the (+)-albendazole S-oxide
-
-
?
1.14.13.32
albendazole + NADPH + O2
-
658526
Ovis aries
(+)-albendazole S-oxide + NADP+
100% enantioselective towards the (+)-albendazole S-oxide
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.14.13.32
flavin
-
Bos taurus
1.14.13.32
flavin
-
Ovis aries
1.14.13.32
NADPH
-
Bos taurus
1.14.13.32
NADPH
-
Ovis aries
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.14.13.32
flavin
-
Bos taurus
1.14.13.32
flavin
-
Ovis aries
1.14.13.32
NADPH
-
Bos taurus
1.14.13.32
NADPH
-
Ovis aries
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.13.32
microsome
-
Bos taurus
-
-
1.14.13.32
microsome
-
Ovis aries
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.13.32
liver
-
Bos taurus
-
1.14.13.32
liver
-
Ovis aries
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.13.32
albendazole + NADPH + O2
-
658526
Bos taurus
(+)-albendazole S-oxide + NADP+
100% enantioselective towards the (+)-albendazole S-oxide
-
-
?
1.14.13.32
albendazole + NADPH + O2
-
658526
Ovis aries
(+)-albendazole S-oxide + NADP+
100% enantioselective towards the (+)-albendazole S-oxide
-
-
?