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Literature summary extracted from

  • Rodrigues-Lima, F.; Cooper, R.N.; Goudeau, B.; Atmane, N.; Chamagne, A.M.; Butler-Browne, G.; Sim, E.; Vicart, P.; Dupret, J.M.
    Skeletal muscles express the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase (2003), J. Histochem. Cytochem., 51, 789-796.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.5 cytoplasm
-
 Homo sapiens 5737
-
2.3.1.5 nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.5 acetyl-CoA + an arylamine Homo sapiens expression of NAT1 in muscle cells may be an important factor in the detoxification/activation process because of the potential involvement of the muscle in the pharmacokinetics of many xenobiotics CoA + a N-acetylarylamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.5 skeletal muscle both NAT2 mRNA and enzyme are readily detected in fetal, newborn, and adult muscles. High expression in fetal muscle. Despite the presence of its mRNA, NAT2 enzyme level is below the limit of detection Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 acetyl-CoA + an arylamine expression of NAT1 in muscle cells may be an important factor in the detoxification/activation process because of the potential involvement of the muscle in the pharmacokinetics of many xenobiotics Homo sapiens CoA + a N-acetylarylamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.5 NAT1
-
 Homo sapiens