Literature summary extracted from

Sorensen, J.L.; Auclair, K.; Kennedy, J.; Hutchinson, C.R.; Vederas, J.C.
Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes (2003), Org. Biomol. Chem., 1, 50-59.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.161	Aspergillus terreus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.161	acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine	reaction catalyzed by Lov B + Loc C. Mutant disruoted at the lovC gene lacks the ability to produce dihydrononacolin L	Aspergillus terreus	dihydromonacolin L + CoA + CO2 + NADP+ + S-adenosyl-L-homocysteine + H2O	-	?

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Release 2023.1 (January 2023)