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Literature summary extracted from

  • Bornemann, D.J.; Duncan, J.E.; Staatz, W.; Selleck, S.; Warrior, R.
    Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways (2004), Development, 131, 1927-198.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.224 additional information enzyme null mutant, dramatically reduced levels of heparan sulfate, impaired Hedgehog, Wingless and Decapentaplegic signalling, alterations in chondroitin sulfate composition and levels Drosophila melanogaster
2.4.1.225 additional information enzyme null mutant, dramatically reduced levels of heparan sulfate, impaired Hedgehog, Wingless and Decapentaplegic signalling, alterations in chondroitin sulfate composition and levels Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.224 Drosophila melanogaster
-
 enzyme sotv, homologue of mammalian EXT2
-
2.4.1.225 Drosophila melanogaster
-
 enzyme sotv, homologue of mammalian EXT2
-

Synonyms

EC Number Synonyms Comment Organism
2.4.1.224 sister of tout velu
-
 Drosophila melanogaster
2.4.1.224 sotv
-
 Drosophila melanogaster
2.4.1.225 sister of tout velu
-
 Drosophila melanogaster
2.4.1.225 sotv
-
 Drosophila melanogaster