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Literature summary extracted from

  • Takahashi-Terada, A.; Kotera, M.; Ohshima, K.; Furumoto, T.; Matsumura, H.; Kai, Y.; Izui, K.
    Maize phosphoenolpyruvate carboxylase. Mutations at the putative binding site for glucose 6-phosphate caused desensitization and abolished responsiveness to regulatory phosphorylation (2005), J. Biol. Chem., 280, 11798-11806.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.31 glucose 6-phosphate activates wild-type enzyme Zea mays
4.1.1.31 glycine allosteric activator Zea mays

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.31
-
 Zea mays

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.31 R183Q mutation results in complete desensitization to glucose 6-phosphate, heterotrophic effect of glucose 6-phosphate on the allosteric inhibitor L-malate is abolished. Sensitivity to the allosteric activator Gly is not affected Zea mays
4.1.1.31 R183Q/R184Q mutation results in complete desensitization to glucose 6-phosphate Zea mays
4.1.1.31 R184Q mutation results in complete desensitization to glucose 6-phosphate Zea mays
4.1.1.31 R372Q mutation results in a marked decrease in sensitivity to glucose 6-phosphate Zea mays

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.31 L-malate inhibits wild-type enzyme Zea mays

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.31 Zea mays
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.31 recombinant Zea mays

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.31 phosphoenolpyruvate + HCO3-
-
 Zea mays phosphate + oxaloacetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.31 PEPC
-
 Zea mays