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Literature summary extracted from
- Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5-phosphosulfate reductase (2006), J. Mol. Biol., 364, 152-169.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.8.4.9 | hanging-drop vapour diffusion | Pseudomonas aeruginosa |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.4.9 | 5'-adenylylsulfate | when thioredoxin concentrations are limiting, elevated concentrations of APS result in inhibition | Pseudomonas aeruginosa |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.8.4.9 | 0.0033 | - |
5'-adenylylsulfate | in the presence of 0.001 mM thioredoxin | Pseudomonas aeruginosa | |
| 1.8.4.9 | 0.0052 | - |
5'-adenylylsulfate | in the presence of 0.01 mM thioredoxin | Pseudomonas aeruginosa | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.4.9 | Pseudomonas aeruginosa | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.4.9 | 5'-adenylylsulfate + glutathione + glutathione | - |
Pseudomonas aeruginosa | adenosine monophosphate + sulfite + oxidized glutathione | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.8.4.9 | tetramer | - |
Pseudomonas aeruginosa |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.4.9 | adenosine 5-phosphosulfate reductase | - |
Pseudomonas aeruginosa |
| 1.8.4.9 | APS reductase | - |
Pseudomonas aeruginosa |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.4.9 | thioredoxin | - |
Pseudomonas aeruginosa | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.8.4.9 | 0.0074 | - |
5'-adenylylsulfate | in the presence of 0.001 mM thioredoxin | Pseudomonas aeruginosa | |
| 1.8.4.9 | 0.081 | - |
5'-adenylylsulfate | in the presence of 0.01 mM thioredoxin | Pseudomonas aeruginosa | |
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Release 2023.1 (January 2023)
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