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Literature summary extracted from
- Energy converting NADH:quinone oxidoreductase (complex I) (2006), Annu. Rev. Biochem., 75, 69-92.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Drosophila melanogaster |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Paracoccus denitrificans |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Chlamydomonas reinhardtii |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Mus musculus |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Thermus thermophilus |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Escherichia coli |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Homo sapiens |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Bos taurus |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Neurospora crassa |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Arabidopsis thaliana |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Yarrowia lipolytica |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Caenorhabditis elegans |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Klebsiella pneumoniae |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Oryza sativa |
| 7.2.1.1 | medicine | about 50% of all mitochondrial disorders affecting the energy metabolism can be traced to mutations in complex 1 | Rhodomonas salina |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.1.1 | Amytal | inhibitor with low affinity | Arabidopsis thaliana |  |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Bos taurus | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Caenorhabditis elegans | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Chlamydomonas reinhardtii | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Drosophila melanogaster | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Escherichia coli | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Homo sapiens | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Klebsiella pneumoniae | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Mus musculus | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Neurospora crassa | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Oryza sativa | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Paracoccus denitrificans | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Rhodomonas salina | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Thermus thermophilus | |
| 7.2.1.1 | Amytal | inhibitor with low affinity | Yarrowia lipolytica | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Arabidopsis thaliana | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Bos taurus | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Caenorhabditis elegans | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Chlamydomonas reinhardtii | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Drosophila melanogaster | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Escherichia coli | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Homo sapiens | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Klebsiella pneumoniae | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Mus musculus | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Neurospora crassa | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Oryza sativa | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Paracoccus denitrificans | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Rhodomonas salina | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Thermus thermophilus | |
| 7.2.1.1 | capsaicin | inhibitor with low affinity | Yarrowia lipolytica | |
| 7.2.1.1 | diphenylene iodonium | - |
Arabidopsis thaliana | |
| 7.2.1.1 | diphenylene iodonium | - |
Bos taurus | |
| 7.2.1.1 | diphenylene iodonium | - |
Caenorhabditis elegans | |
| 7.2.1.1 | diphenylene iodonium | - |
Chlamydomonas reinhardtii | |
| 7.2.1.1 | diphenylene iodonium | - |
Drosophila melanogaster | |
| 7.2.1.1 | diphenylene iodonium | - |
Escherichia coli | |
| 7.2.1.1 | diphenylene iodonium | - |
Homo sapiens | |
| 7.2.1.1 | diphenylene iodonium | - |
Klebsiella pneumoniae | |
| 7.2.1.1 | diphenylene iodonium | - |
Mus musculus | |
| 7.2.1.1 | diphenylene iodonium | - |
Neurospora crassa | |
| 7.2.1.1 | diphenylene iodonium | - |
Oryza sativa | |
| 7.2.1.1 | diphenylene iodonium | - |
Paracoccus denitrificans | |
| 7.2.1.1 | diphenylene iodonium | - |
Rhodomonas salina | |
| 7.2.1.1 | diphenylene iodonium | - |
Thermus thermophilus | |
| 7.2.1.1 | diphenylene iodonium | - |
Yarrowia lipolytica | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Arabidopsis thaliana | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Bos taurus | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Caenorhabditis elegans | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Chlamydomonas reinhardtii | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Drosophila melanogaster | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Escherichia coli | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Homo sapiens | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Klebsiella pneumoniae | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Mus musculus | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Neurospora crassa | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Oryza sativa | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Paracoccus denitrificans | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Rhodomonas salina | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Thermus thermophilus | |
| 7.2.1.1 | meperidin | inhibitor with low affinity | Yarrowia lipolytica | |
| 7.2.1.1 | Piericidin A | - |
Bos taurus | |
| 7.2.1.1 | rolliniastatin-1 | - |
Bos taurus | |
| 7.2.1.1 | rotenone | - |
Bos taurus | |
| 7.2.1.1 | Thesit | specific inhibition | Arabidopsis thaliana | |
| 7.2.1.1 | Thesit | specific inhibition | Bos taurus | |
| 7.2.1.1 | Thesit | specific inhibition | Caenorhabditis elegans | |
| 7.2.1.1 | Thesit | specific inhibition | Chlamydomonas reinhardtii | |
| 7.2.1.1 | Thesit | specific inhibition | Drosophila melanogaster | |
| 7.2.1.1 | Thesit | specific inhibition | Escherichia coli | |
| 7.2.1.1 | Thesit | specific inhibition | Homo sapiens | |
| 7.2.1.1 | Thesit | specific inhibition | Klebsiella pneumoniae | |
| 7.2.1.1 | Thesit | specific inhibition | Mus musculus | |
| 7.2.1.1 | Thesit | specific inhibition | Neurospora crassa | |
| 7.2.1.1 | Thesit | specific inhibition | Oryza sativa | |
| 7.2.1.1 | Thesit | specific inhibition | Paracoccus denitrificans | |
| 7.2.1.1 | Thesit | specific inhibition | Rhodomonas salina | |
| 7.2.1.1 | Thesit | specific inhibition | Thermus thermophilus | |
| 7.2.1.1 | Thesit | specific inhibition | Yarrowia lipolytica | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Arabidopsis thaliana | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Bos taurus | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Caenorhabditis elegans | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Chlamydomonas reinhardtii | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Drosophila melanogaster | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Escherichia coli | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Homo sapiens | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Klebsiella pneumoniae | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Mus musculus | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Neurospora crassa | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Oryza sativa | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Paracoccus denitrificans | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Rhodomonas salina | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Thermus thermophilus | |
| 7.2.1.1 | Triton X-100 | specific inhibition | Yarrowia lipolytica | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.2.1.1 | mitochondrion | - |
Drosophila melanogaster | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Mus musculus | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Escherichia coli | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Homo sapiens | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Bos taurus | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Caenorhabditis elegans | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Klebsiella pneumoniae | 5739 | - |
| 7.2.1.1 | mitochondrion | - |
Oryza sativa | 5739 | - |
| 7.2.1.1 | plasma membrane | - |
Paracoccus denitrificans | 5886 | - |
| 7.2.1.1 | plasma membrane | - |
Chlamydomonas reinhardtii | 5886 | - |
| 7.2.1.1 | plasma membrane | - |
Thermus thermophilus | 5886 | - |
| 7.2.1.1 | plasma membrane | - |
Neurospora crassa | 5886 | - |
| 7.2.1.1 | plasma membrane | - |
Yarrowia lipolytica | 5886 | - |
| 7.2.1.1 | plasma membrane | - |
Rhodomonas salina | 5886 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Drosophila melanogaster | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Paracoccus denitrificans | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Chlamydomonas reinhardtii | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Mus musculus | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Thermus thermophilus | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Escherichia coli | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Homo sapiens | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Bos taurus | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Neurospora crassa | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Arabidopsis thaliana | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Yarrowia lipolytica | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Caenorhabditis elegans | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Klebsiella pneumoniae | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Oryza sativa | |
| 7.2.1.1 | Iron | contains 8 to 9 iron-sulfur clusters | Rhodomonas salina | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.1.1 | NADH + ubiquinone-1 | Drosophila melanogaster | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Paracoccus denitrificans | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Chlamydomonas reinhardtii | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Mus musculus | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Thermus thermophilus | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Escherichia coli | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Homo sapiens | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Bos taurus | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Neurospora crassa | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Arabidopsis thaliana | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Yarrowia lipolytica | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Caenorhabditis elegans | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Klebsiella pneumoniae | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | Oryza sativa | - |
NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Drosophila melanogaster | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Paracoccus denitrificans | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Chlamydomonas reinhardtii | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Mus musculus | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Thermus thermophilus | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Escherichia coli | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Homo sapiens | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Bos taurus | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Neurospora crassa | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Arabidopsis thaliana | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Yarrowia lipolytica | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Caenorhabditis elegans | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Klebsiella pneumoniae | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | Oryza sativa | - |
NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Drosophila melanogaster | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Paracoccus denitrificans | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Chlamydomonas reinhardtii | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Mus musculus | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Thermus thermophilus | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Escherichia coli | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Homo sapiens | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Bos taurus | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Neurospora crassa | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Arabidopsis thaliana | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Yarrowia lipolytica | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Caenorhabditis elegans | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Klebsiella pneumoniae | - |
NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | Oryza sativa | - |
NAD+ + ubiquinol-9 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.2.1.1 | Arabidopsis thaliana | - |
- |
- |
| 7.2.1.1 | Bos taurus | - |
- |
- |
| 7.2.1.1 | Caenorhabditis elegans | - |
- |
- |
| 7.2.1.1 | Chlamydomonas reinhardtii | - |
- |
- |
| 7.2.1.1 | Drosophila melanogaster | - |
- |
- |
| 7.2.1.1 | Escherichia coli | - |
- |
- |
| 7.2.1.1 | Homo sapiens | - |
- |
- |
| 7.2.1.1 | Klebsiella pneumoniae | - |
- |
- |
| 7.2.1.1 | Mus musculus | - |
- |
- |
| 7.2.1.1 | Neurospora crassa | - |
- |
- |
| 7.2.1.1 | Oryza sativa | - |
- |
- |
| 7.2.1.1 | Paracoccus denitrificans | - |
- |
- |
| 7.2.1.1 | Rhodomonas salina | - |
- |
- |
| 7.2.1.1 | Thermus thermophilus | - |
- |
- |
| 7.2.1.1 | Yarrowia lipolytica | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.1.1 | NADH + menaquinone | - |
Drosophila melanogaster | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Paracoccus denitrificans | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Chlamydomonas reinhardtii | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Mus musculus | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Thermus thermophilus | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Escherichia coli | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Homo sapiens | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Bos taurus | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Neurospora crassa | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Arabidopsis thaliana | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Yarrowia lipolytica | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Caenorhabditis elegans | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Klebsiella pneumoniae | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Oryza sativa | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + menaquinone | - |
Rhodomonas salina | NAD+ + reduced menaquinone | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Drosophila melanogaster | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Paracoccus denitrificans | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Chlamydomonas reinhardtii | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Mus musculus | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Thermus thermophilus | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Escherichia coli | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Homo sapiens | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Bos taurus | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Neurospora crassa | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Arabidopsis thaliana | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Yarrowia lipolytica | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Caenorhabditis elegans | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Klebsiella pneumoniae | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Oryza sativa | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-1 | - |
Rhodomonas salina | NAD+ + ubiquinol-1 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Drosophila melanogaster | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Paracoccus denitrificans | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Chlamydomonas reinhardtii | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Mus musculus | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Thermus thermophilus | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Escherichia coli | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Homo sapiens | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Bos taurus | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Neurospora crassa | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Arabidopsis thaliana | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Yarrowia lipolytica | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Caenorhabditis elegans | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Klebsiella pneumoniae | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Oryza sativa | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-10 | - |
Rhodomonas salina | NAD+ + ubiquinol-10 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Drosophila melanogaster | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Paracoccus denitrificans | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Chlamydomonas reinhardtii | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Mus musculus | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Thermus thermophilus | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Escherichia coli | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Homo sapiens | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Bos taurus | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Neurospora crassa | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Arabidopsis thaliana | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Yarrowia lipolytica | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Caenorhabditis elegans | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Klebsiella pneumoniae | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Oryza sativa | NAD+ + ubiquinol-9 | - |
? | |
| 7.2.1.1 | NADH + ubiquinone-9 | - |
Rhodomonas salina | NAD+ + ubiquinol-9 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Drosophila melanogaster |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Paracoccus denitrificans |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Chlamydomonas reinhardtii |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Mus musculus |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Thermus thermophilus |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Escherichia coli |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Homo sapiens |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Bos taurus |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Neurospora crassa |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Arabidopsis thaliana |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Yarrowia lipolytica |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Caenorhabditis elegans |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Klebsiella pneumoniae |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Oryza sativa |
| 7.2.1.1 | More | contains 14 central subunits and 32 accessory subunits | Rhodomonas salina |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.2.1.1 | complex I | - |
Drosophila melanogaster |
| 7.2.1.1 | complex I | - |
Paracoccus denitrificans |
| 7.2.1.1 | complex I | - |
Chlamydomonas reinhardtii |
| 7.2.1.1 | complex I | - |
Mus musculus |
| 7.2.1.1 | complex I | - |
Thermus thermophilus |
| 7.2.1.1 | complex I | - |
Escherichia coli |
| 7.2.1.1 | complex I | - |
Homo sapiens |
| 7.2.1.1 | complex I | - |
Bos taurus |
| 7.2.1.1 | complex I | - |
Neurospora crassa |
| 7.2.1.1 | complex I | - |
Arabidopsis thaliana |
| 7.2.1.1 | complex I | - |
Yarrowia lipolytica |
| 7.2.1.1 | complex I | - |
Caenorhabditis elegans |
| 7.2.1.1 | complex I | - |
Klebsiella pneumoniae |
| 7.2.1.1 | complex I | - |
Oryza sativa |
| 7.2.1.1 | complex I | - |
Rhodomonas salina |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Drosophila melanogaster |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Paracoccus denitrificans |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Chlamydomonas reinhardtii |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Mus musculus |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Thermus thermophilus |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Escherichia coli |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Homo sapiens |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Bos taurus |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Neurospora crassa |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Arabidopsis thaliana |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Yarrowia lipolytica |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Caenorhabditis elegans |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Klebsiella pneumoniae |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Oryza sativa |
| 7.2.1.1 | NADH:quinone oxidoreductase | - |
Rhodomonas salina |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.1.1 | FAD | - |
Drosophila melanogaster | |
| 7.2.1.1 | FAD | - |
Paracoccus denitrificans | |
| 7.2.1.1 | FAD | - |
Chlamydomonas reinhardtii | |
| 7.2.1.1 | FAD | - |
Mus musculus | |
| 7.2.1.1 | FAD | - |
Thermus thermophilus | |
| 7.2.1.1 | FAD | - |
Escherichia coli | |
| 7.2.1.1 | FAD | - |
Homo sapiens | |
| 7.2.1.1 | FAD | - |
Bos taurus | |
| 7.2.1.1 | FAD | - |
Neurospora crassa | |
| 7.2.1.1 | FAD | - |
Arabidopsis thaliana | |
| 7.2.1.1 | FAD | - |
Yarrowia lipolytica | |
| 7.2.1.1 | FAD | - |
Caenorhabditis elegans | |
| 7.2.1.1 | FAD | - |
Klebsiella pneumoniae | |
| 7.2.1.1 | FAD | - |
Oryza sativa | |
| 7.2.1.1 | FAD | - |
Rhodomonas salina | |
| 7.2.1.1 | FMN | - |
Drosophila melanogaster | |
| 7.2.1.1 | FMN | - |
Paracoccus denitrificans | |
| 7.2.1.1 | FMN | - |
Chlamydomonas reinhardtii | |
| 7.2.1.1 | FMN | - |
Mus musculus | |
| 7.2.1.1 | FMN | - |
Thermus thermophilus | |
| 7.2.1.1 | FMN | - |
Escherichia coli | |
| 7.2.1.1 | FMN | - |
Homo sapiens | |
| 7.2.1.1 | FMN | - |
Bos taurus | |
| 7.2.1.1 | FMN | - |
Neurospora crassa | |
| 7.2.1.1 | FMN | - |
Arabidopsis thaliana | |
| 7.2.1.1 | FMN | - |
Yarrowia lipolytica | |
| 7.2.1.1 | FMN | - |
Caenorhabditis elegans | |
| 7.2.1.1 | FMN | - |
Klebsiella pneumoniae | |
| 7.2.1.1 | FMN | - |
Oryza sativa | |
| 7.2.1.1 | FMN | - |
Rhodomonas salina | |
| 7.2.1.1 | NADH | - |
Drosophila melanogaster | |
| 7.2.1.1 | NADH | - |
Paracoccus denitrificans | |
| 7.2.1.1 | NADH | - |
Chlamydomonas reinhardtii | |
| 7.2.1.1 | NADH | - |
Mus musculus | |
| 7.2.1.1 | NADH | - |
Thermus thermophilus | |
| 7.2.1.1 | NADH | - |
Escherichia coli | |
| 7.2.1.1 | NADH | - |
Homo sapiens | |
| 7.2.1.1 | NADH | - |
Bos taurus | |
| 7.2.1.1 | NADH | - |
Neurospora crassa | |
| 7.2.1.1 | NADH | - |
Arabidopsis thaliana | |
| 7.2.1.1 | NADH | - |
Yarrowia lipolytica | |
| 7.2.1.1 | NADH | - |
Caenorhabditis elegans | |
| 7.2.1.1 | NADH | - |
Klebsiella pneumoniae | |
| 7.2.1.1 | NADH | - |
Oryza sativa | |
| 7.2.1.1 | NADH | - |
Rhodomonas salina | |
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Release 2023.1 (January 2023)
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